Literature DB >> 34716027

Dynamic regulation of gut Clostridium-derived short-chain fatty acids.

Zhengming Zhu1, Liying Zhu2, Ling Jiang3.   

Abstract

Short-chain fatty acids (SCFAs) are major products of intestinal microbial fermentation with beneficial effects for human health. The dynamic balance and real-time monitoring of endogenous SCFA biosynthesis are important for understanding their physiological functions. We discuss the promising future of applying CRISPRi genetic systems and biosensors for targeted SCFA improvement.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  CRISPRi genetic system; biosensor; gut Clostridium; short-chain fatty acids; synthetic biology

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Year:  2021        PMID: 34716027     DOI: 10.1016/j.tibtech.2021.10.005

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  2 in total

Review 1.  Gut microbiome-produced metabolites in pigs: a review on their biological functions and the influence of probiotics.

Authors:  Robie Vasquez; Ju Kyoung Oh; Ji Hoon Song; Dae-Kyung Kang
Journal:  J Anim Sci Technol       Date:  2022-07-31

2.  Functional Characterization of Clostridium tyrobutyricum L319: A Promising Next-Generation Probiotic for Short-Chain Fatty Acid Production.

Authors:  Zhihan Yang; Fatima Ezzahra Amal; Lei Yang; Yuxin Liu; Liying Zhu; Zhengming Zhu; Ling Jiang
Journal:  Front Microbiol       Date:  2022-06-17       Impact factor: 6.064

  2 in total

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