| Literature DB >> 34714553 |
Sharon Elad1, Noam Yarom2,3, Yehuda Zadik4,5, Michal Kuten-Shorrer1,6, Stephen T Sonis7,8.
Abstract
Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that affects patients' function, quality of life, and ability to tolerate treatment. In certain patients with cancer, OM is associated with increased mortality. Research on the management of OM is ongoing. Oral mucosal toxicities are also reported in targeted and immune checkpoint inhibitor therapies. The objective of this article is to present current knowledge about the epidemiology, pathogenesis, assessment, risk prediction, and current and developing intervention strategies for OM and other ulcerative mucosal toxicities caused by both conventional and evolving forms of cancer therapy.Entities:
Keywords: cancer; immune checkpoint inhibitors; immunotherapy; oral mucositis; stomatitis; targeted therapy; toxicity; ulcer
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Year: 2021 PMID: 34714553 DOI: 10.3322/caac.21704
Source DB: PubMed Journal: CA Cancer J Clin ISSN: 0007-9235 Impact factor: 508.702