Literature DB >> 34714553

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies.

Sharon Elad1, Noam Yarom2,3, Yehuda Zadik4,5, Michal Kuten-Shorrer1,6, Stephen T Sonis7,8.   

Abstract

Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that affects patients' function, quality of life, and ability to tolerate treatment. In certain patients with cancer, OM is associated with increased mortality. Research on the management of OM is ongoing. Oral mucosal toxicities are also reported in targeted and immune checkpoint inhibitor therapies. The objective of this article is to present current knowledge about the epidemiology, pathogenesis, assessment, risk prediction, and current and developing intervention strategies for OM and other ulcerative mucosal toxicities caused by both conventional and evolving forms of cancer therapy.
© 2021 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society.

Entities:  

Keywords:  cancer; immune checkpoint inhibitors; immunotherapy; oral mucositis; stomatitis; targeted therapy; toxicity; ulcer

Mesh:

Substances:

Year:  2021        PMID: 34714553     DOI: 10.3322/caac.21704

Source DB:  PubMed          Journal:  CA Cancer J Clin        ISSN: 0007-9235            Impact factor:   508.702


  3 in total

1.  Protective Effects of Cannabidiol on Chemotherapy-Induced Oral Mucositis via the Nrf2/Keap1/ARE Signaling Pathways.

Authors:  Lin Li; Yaowei Xuan; Biao Zhu; Xing Wang; Xiaoyu Tian; Lisheng Zhao; Yan Wang; Xiaoxia Jiang; Ning Wen
Journal:  Oxid Med Cell Longev       Date:  2022-05-25       Impact factor: 7.310

Review 2.  Natural Products for the Prevention and Treatment of Oral Mucositis-A Review.

Authors:  Ana Sofia Ferreira; Catarina Macedo; Ana Margarida Silva; Cristina Delerue-Matos; Paulo Costa; Francisca Rodrigues
Journal:  Int J Mol Sci       Date:  2022-04-15       Impact factor: 6.208

Review 3.  Precision medicine for risk prediction of oral complications of cancer therapy-The example of oral mucositis in patients receiving radiation therapy for cancers of the head and neck.

Authors:  Stephen T Sonis
Journal:  Front Oral Health       Date:  2022-08-18
  3 in total

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