Literature DB >> 34713700

Aqueous and Visible-Light-Promoted C-H (Hetero)arylation of Uracil Derivatives with Diazoniums.

An-Di Liu1,2, Zhao-Li Wang3,2, Li Liu1,2, Liang Cheng1,3,2.   

Abstract

Direct C5 (hetero)arylation of uracil and uridine substrates with (hetero)aryl diazonium salts under photoredox catalysis with blue light was reported. The coupling proceeds efficiently with diazonium salts and heterocycles in good functional group tolerance at room temperature in aqueous solution without transition-metal components. A plausible radical mechanism has been proposed.

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Year:  2021        PMID: 34713700     DOI: 10.1021/acs.joc.1c01799

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Palladium-catalyzed C-H olefination of uridine, deoxyuridine, uridine monophosphate and uridine analogues.

Authors:  Qin Zhao; Ruoqian Xie; Yuxiao Zeng; Wanlu Li; Guolan Xiao; Yangyan Li; Gang Chen
Journal:  RSC Adv       Date:  2022-09-01       Impact factor: 4.036

  1 in total

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