Literature DB >> 34711630

Taming the Wild-Type Gastrointestinal Stromal Tumor: Improved Tissue Culture.

Andrew M Blakely1, John W Glod2, Mary Frances Wedekind Malone2.   

Abstract

Wild-type gastrointestinal stromal tumors (WT GIST) are most frequently characterized by succinate dehydrogenase (SDH) deficiency. Reliable ex vivo tumor models have been difficult to develop given the downstream metabolic effects of SDH deficiency. Improved tumor modeling approaches are needed to develop effective systemic treatment options for patients with WT GIST.See related article by Yebra et al., p. 187. ©2021 American Association for Cancer Research.

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Year:  2021        PMID： 34711630      PMCID： PMC8738134          DOI： 10.1158/1078-0432.CCR-21-3409

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   13.801


  5 in total

1.  Conventional and molecular cytogenetic characterization of a new human cell line, GIST-T1, established from gastrointestinal stromal tumor.

Authors:  Takahiro Taguchi; Hiroshi Sonobe; Shin-ichi Toyonaga; Ichiro Yamasaki; Taro Shuin; Atsushi Takano; Keijiro Araki; Kunihiro Akimaru; Kazunari Yuri
Journal:  Lab Invest       Date:  2002-05       Impact factor: 5.662

2.  A unique model for SDH-deficient GIST: an endocrine-related cancer.

Authors:  James F Powers; Brent Cochran; James D Baleja; Hadley D Sikes; Xue Zhang; Inna Lomakin; Troy Langford; Kassi Taylor Stein; Arthur S Tischler
Journal:  Endocr Relat Cancer       Date:  2018-07-02       Impact factor: 5.678

Review 3.  3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening.

Authors:  Joseph Vanderburgh; Julie A Sterling; Scott A Guelcher
Journal:  Ann Biomed Eng       Date:  2016-05-11       Impact factor: 3.934

4.  Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic.

Authors:  Sosipatros A Boikos; Alberto S Pappo; J Keith Killian; Michael P LaQuaglia; Chris B Weldon; Suzanne George; Jonathan C Trent; Margaret von Mehren; Jennifer A Wright; Josh D Schiffman; Margarita Raygada; Karel Pacak; Paul S Meltzer; Markku M Miettinen; Constantine Stratakis; Katherine A Janeway; Lee J Helman
Journal:  JAMA Oncol       Date:  2016-07-01       Impact factor: 31.777

5.  Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response.

Authors:  Mayra Yebra; Shruti Bhargava; Avi Kumar; Adam M Burgoyne; Chih-Min Tang; Hyunho Yoon; Sudeep Banerjee; Joseph Aguilera; Thekla Cordes; Vipul Sheth; Sangkyu Noh; Rowan Ustoy; Sam Li; Sunil J Advani; Christopher L Corless; Michael C Heinrich; Razelle Kurzrock; Scott M Lippman; Paul T Fanta; Olivier Harismendy; Christian Metallo; Jason K Sicklick
Journal:  Clin Cancer Res       Date:  2021-08-23       Impact factor: 13.801
  5 in total

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