Literature DB >> 34709536

Robotic radical hysterectomy versus open radical hysterectomy for cervical cancer: a single-centre experience from India.

Rupinder Sekhon1, Amita Naithani2, Priyanka Makkar1, Pratima R1, Parul Sharma1, Sudhir Rawal1, Yuvraj Goyal1, Swarupa Mitra1, Anila Sharma1, Anurag Mehta1.   

Abstract

To compare the disease-free survival (DFS) and overall survival (OS) at 3 years and 5 years in patients undergoing treatment for early-stage cervical cancer with either robotic (RRH) or open radical hysterectomy (ORH). This retrospective study compared all patients with stage IA1 (lymphovascular invasion), IA2, IB1, IB2 and II A cervical cancer in accordance with International Federation of Gynaecology and Obstetrics staging (FIGO 2009) of cancer of the cervix uteri. Patients who underwent Radical Hysterectomy at our centre from January 2011 till January 2018 were included in the study. One hundred and eighty-nine patients ( ORH = 67, RRH = 122) were included. The median follow-up time was 46.3 months in RRH group and 70.0 months in the ORH group. The 3-year DFS was comparable in both the arms, 91.5% in RRH and 91.6% in ORH. The 5-year DFS was 88.9% and 85.9% in robotic and open approaches, respectively (P = 0.258), hazard ratio (HR) 0.616 (CI = 0.266-1.427). The 3-year overall survival for robotic approach was 93.4% and for open was 95%, whereas 5-year overall survival was 84.7% and 87.4% in robotic and open approaches, respectively (P = 0.813). The median estimated blood loss for robotics was lower (100 ml vs 300 ml, P < 0.001) and median operative time was less (162.5 min vs. 180 min, P = 0.005) in robotics. The patients in RRH cohort had shorter median hospital stay (3.9 days vs. 6.3 days, P < 0.001). Robotic radical hysterectomy had comparable survival outcomes to open radical hysterectomy in cancer cervix. RRH is associated with improved peri-operative surgical outcomes and better resource utilisation.
© 2021. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.

Entities:  

Keywords:  Cancer cervix; Open radical hysterectomy; Robotic radical hysterectomy; Survival outcomes

Mesh:

Year:  2021        PMID: 34709536     DOI: 10.1007/s11701-021-01320-6

Source DB:  PubMed          Journal:  J Robot Surg        ISSN: 1863-2483


  11 in total

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Authors:  Sergio Pecorelli; Lucia Zigliani; Franco Odicino
Journal:  Int J Gynaecol Obstet       Date:  2009-04-01       Impact factor: 3.561

2.  Robot-assisted approach to cervical cancer (RACC): an international multi-center, open-label randomized controlled trial.

Authors:  Henrik Falconer; Kolbrun Palsdottir; Karin Stalberg; Pernilla Dahm-Kähler; Ulrika Ottander; Evelyn Serreyn Lundin; Lena Wijk; Rainer Kimmig; Pernille Tine Jensen; Ane Gerda Zahl Eriksson; Johanna Mäenpää; Jan Persson; Sahar Salehi
Journal:  Int J Gynecol Cancer       Date:  2019-06-14       Impact factor: 3.437

3.  No survival difference between robotic and open radical hysterectomy for women with early-stage cervical cancer: results from a nationwide population-based cohort study.

Authors:  Emilia Alfonzo; Emelie Wallin; Linnea Ekdahl; Christian Staf; Angelique Flöter Rådestad; Petur Reynisson; Karin Stålberg; Henrik Falconer; Jan Persson; Pernilla Dahm-Kähler
Journal:  Eur J Cancer       Date:  2019-06-11       Impact factor: 9.162

4.  Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer.

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5.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.

Authors:  Hyuna Sung; Jacques Ferlay; Rebecca L Siegel; Mathieu Laversanne; Isabelle Soerjomataram; Ahmedin Jemal; Freddie Bray
Journal:  CA Cancer J Clin       Date:  2021-02-04       Impact factor: 508.702

6.  Survival after Minimally Invasive Radical Hysterectomy for Early-Stage Cervical Cancer.

Authors:  Alexander Melamed; Daniel J Margul; Ling Chen; Nancy L Keating; Marcela G Del Carmen; Junhua Yang; Brandon-Luke L Seagle; Amy Alexander; Emma L Barber; Laurel W Rice; Jason D Wright; Masha Kocherginsky; Shohreh Shahabi; J Alejandro Rauh-Hain
Journal:  N Engl J Med       Date:  2018-10-31       Impact factor: 91.245

7.  Robot-assisted versus open radical hysterectomy: A multi-institutional experience for early-stage cervical cancer.

Authors:  B M Sert; J F Boggess; S Ahmad; A L Jackson; N M Stavitzski; A A Dahl; R W Holloway
Journal:  Eur J Surg Oncol       Date:  2016-01-21       Impact factor: 4.424

Review 8.  Primary management of early stage cervical cancer (IA1-IB) and appropriate selection of adjuvant therapy.

Authors:  Heidi J Gray
Journal:  J Natl Compr Canc Netw       Date:  2008-01       Impact factor: 11.908

9.  Minimally invasive versus open radical trachelectomy for early-stage cervical cancer: protocol for a multicenter randomized controlled trial in China.

Authors:  Xiaopei Chao; Lei Li; Ming Wu; Huanwen Wu; Shuiqing Ma; Xianjie Tan; Sen Zhong; Jinghe Lang
Journal:  Trials       Date:  2020-12-14       Impact factor: 2.279

10.  Surgical and oncologic outcomes after robotic radical hysterectomy as compared to open radical hysterectomy in the treatment of early cervical cancer.

Authors:  Chirag A Shah; Tiffany Beck; John B Liao; Nadia V Giannakopoulos; Dan Veljovich; Pam Paley
Journal:  J Gynecol Oncol       Date:  2017-11       Impact factor: 4.401

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