Literature DB >> 34705182

Rat Blood Leukocytes after Intravenous Injection of Magnetoliposomes on the Basis of Nanomagnetite.

I V Mil'to1,2, V V Ivanova3, N M Shevtsova3, O N Serebryakova3, A A Ivanov4, E A Gereng3, R M Takhauov5, I V Sukhodolo3.   

Abstract

The structure of blood neutrophils, eosinophils, monocytes, and lymphocytes and differential white blood count in adult rats were studied over 120 days after a single intravenous injection of magnetoliposomes based on nanomagnetite. Magnetoliposomes had no effect on the structure of neutrophils, eosinophils, monocytes, and lymphocytes. At the same time, injection of a suspension of magnetoliposomes based on magnetite nanoparticles led to a decrease in lymphocyte count and an increase in the count of monocytes and band and segmented neutrophils in the blood. These changes were transient and the parameters returned to normal by day 40-60 after injection.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  blood leukocytes; magnetoliposomes; nanomagnetite; rats

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Year:  2021        PMID: 34705182     DOI: 10.1007/s10517-021-05314-0

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  4 in total

1.  Magnetic nanoparticles-loaded liposomes as a novel treatment agent for iron deficiency anemia: In vivo study.

Authors:  Mohamed M Fathy; Heba M Fahmy; Asmaa M M Balah; Faten F Mohamed; Wael M Elshemey
Journal:  Life Sci       Date:  2019-08-21       Impact factor: 5.037

2.  Formulation and in vitro evaluation of magnetoliposomes as a potential nanotool in colorectal cancer therapy.

Authors:  Cristina Lorente; Laura Cabeza; Beatriz Clares; Raúl Ortiz; Lyda Halbaut; Ángel V Delgado; Gloria Perazzoli; José Prados; José L Arias; Consolación Melguizo
Journal:  Colloids Surf B Biointerfaces       Date:  2018-07-31       Impact factor: 5.268

3.  Size-dependent superparamagnetic iron oxide nanoparticles dictate interleukin-1β release from mouse bone marrow-derived macrophages.

Authors:  Shuzhen Chen; Suyun Chen; Yun Zeng; Lin Lin; Chuang Wu; Yanyan Ke; Gang Liu
Journal:  J Appl Toxicol       Date:  2018-02-28       Impact factor: 3.446

4.  Targeted liposomal drug delivery to monocytes and macrophages.

Authors:  Ciara Kelly; Caroline Jefferies; Sally-Ann Cryan
Journal:  J Drug Deliv       Date:  2010-10-26
  4 in total

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