Literature DB >> 34705176

Study of the Dynamics of Biofilm Formation and Elastase Activity of Pseudomonas aeruginosa in the Presence of Dodecanoyl-Homoserine Lactone.

V S Cherepushkina1, T E Mironova2,3, V N Afonyushkin2,4, V Yu Koptev2, E V Nefedova2, N A Donchenko2,3, A S Dimova3.   

Abstract

We studied the effect of early accumulation of N-3-oxo-dodecanoyl-homoserine lactone on the suppression of Pseudomonas aeruginosa reproduction, biofilm formation, and elastase activity. N-3-oxo-dodecanoyl-homoserine lactone in various concentrations was added to the P. aeruginosa culture, and changes in the concentration of bacteria and the formation of biofilms were studied in dynamics. N-3-oxo-dodecanoyl-homoserine lactone in a concentration of 25 μM, decelerated proliferation of bacterial cells during the first 6 h of culturing (p<0.05) and stimulated biofilm formation after 18 h of culturing. Elastase activity of P. aeruginosa increased significantly after addition of N-3-oxo-dodecanoyl-homoserine lactone in a concentration of 0.75 μM.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  N-3-oxo-dodecanoyl-homoserine lactone; Pseudomonas aeruginosa; biofilms; elastase

Mesh：

Substances：

Year:  2021        PMID： 34705176     DOI： 10.1007/s10517-021-05307-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  7 in total

Review 1.  The use of molecular typing for epidemiological surveillance and investigation of endemic nosocomial infections.

Authors:  Dominique S Blanc
Journal:  Infect Genet Evol       Date:  2004-09       Impact factor: 3.342

2.  Nonenzymatic turnover of an Erwinia carotovora quorum-sensing signaling molecule.

Authors:  Joseph T Byers; Claire Lucas; George P C Salmond; Martin Welch
Journal:  J Bacteriol       Date:  2002-02       Impact factor: 3.490

3.  N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa.

Authors:  Edwin A Yates; Bodo Philipp; Catherine Buckley; Steve Atkinson; Siri Ram Chhabra; R Elizabeth Sockett; Morris Goldner; Yves Dessaux; Miguel Cámara; Harry Smith; Paul Williams
Journal:  Infect Immun       Date:  2002-10       Impact factor: 3.441

4.  Pseudomonas aeruginosa in a neonatal intensive care unit: reservoirs and ecology of the nosocomial pathogen.

Authors:  H Grundmann; A Kropec; D Hartung; R Berner; F Daschner
Journal:  J Infect Dis       Date:  1993-10       Impact factor: 5.226

5.  The application of biofilm science to the study and control of chronic bacterial infections.

Authors:  William Costerton; Richard Veeh; Mark Shirtliff; Mark Pasmore; Christopher Post; Garth Ehrlich
Journal:  J Clin Invest       Date:  2003-11       Impact factor: 14.808

6.  Selection for increased quorum-sensing cooperation in Pseudomonas aeruginosa through the shut-down of a drug resistance pump.

Authors:  Ron D Oshri; Keren S Zrihen; Itzhak Shner; Shira Omer Bendori; Avigdor Eldar
Journal:  ISME J       Date:  2018-06-20       Impact factor: 10.302

Review 7.  Antimicrobial resistance in the food chain: a review.

Authors:  Claire Verraes; Sigrid Van Boxstael; Eva Van Meervenne; Els Van Coillie; Patrick Butaye; Boudewijn Catry; Marie-Athénaïs de Schaetzen; Xavier Van Huffel; Hein Imberechts; Katelijne Dierick; George Daube; Claude Saegerman; Jan De Block; Jeroen Dewulf; Lieve Herman
Journal:  Int J Environ Res Public Health       Date:  2013-06-28       Impact factor: 3.390
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.