Literature DB >> 34705173

Functioning of the Antioxidant Defense System in Rotenone-Induced Parkinson's Disease.

E D Kryl'skii1, G A Razuvaev2, T N Potapova2, A I Akinina2, L E Nihaev2.   

Abstract

A comprehensive study of the functioning of antioxidant system in rats with rotenone-induced parkinsonism was conducted. The development of pathology led to inhibition of the majority of the studied antioxidant enzymes in the brain and blood serum of animals, which can be associated with decompensation of oxidative stress under conditions of prolonged mitochondrial dysfunction. These changes apparently make an important contribution into neuronal degeneration in the cerebral cortex and striatum and motor disorders in experimental animals.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Parkinson’s disease; antioxidant system; oxidative stress; rotenone

Mesh：

Substances：

Year:  2021        PMID： 34705173     DOI： 10.1007/s10517-021-05302-4

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  9 in total

1.  A simple method for determination of serum catalase activity and revision of reference range.

Authors:  L Góth
Journal:  Clin Chim Acta       Date:  1991-02-15       Impact factor: 3.786

2.  Plasma lipid peroxidation and antioxidant status of Parkinson's disease patients in the Indian population.

Authors:  Aabha Sharma; Pushpinder Kaur; Binu Kumar; S Prabhakar; K D Gill
Journal:  Parkinsonism Relat Disord       Date:  2007-11-26       Impact factor: 4.891

3.  Transcriptional Regulation of Antioxidant Enzymes Activity and Modulation of Oxidative Stress by Melatonin in Rats Under Cerebral Ischemia / Reperfusion Conditions.

Authors:  Evgenii D Kryl'skii; Tatyana N Popova; Olga A Safonova; Anna O Stolyarova; Grigorii A Razuvaev; Miguel Angelo Pinheiro de Carvalho
Journal:  Neuroscience       Date:  2019-02-01       Impact factor: 3.590

4.  Serum glutathione peroxidase, xanthine oxidase, and superoxide dismutase activities and malondialdehyde levels in patients with Parkinson's disease.

Authors:  Burcu Gökçe Çokal; Mustafa Yurtdaş; Selda Keskin Güler; Hafize Nalan Güneş; Ceyla Ataç Uçar; Bilal Aytaç; Zahide Esra Durak; Tahir Kurtuluş Yoldaş; İlker Durak; Hikmet Can Çubukçu
Journal:  Neurol Sci       Date:  2016-11-30       Impact factor: 3.307

Review 5.  Damage to dopaminergic neurons by oxidative stress in Parkinson's disease (Review).

Authors:  Ji-Dong Guo; Xin Zhao; Yang Li; Guang-Ren Li; Xiao-Liang Liu
Journal:  Int J Mol Med       Date:  2018-01-19       Impact factor: 4.101

6.  [Investigation of Free Radical Processes in Substrates and Biological Samples by Means of induced Chemiluminescence].

Authors:  I M Piskarev; S V Trofimova; O E Burkhina; I P Ivanova
Journal:  Biofizika       Date:  2015 May-Jun

Review 7.  The genetic architecture of Parkinson's disease.

Authors:  Cornelis Blauwendraat; Mike A Nalls; Andrew B Singleton
Journal:  Lancet Neurol       Date:  2019-09-11       Impact factor: 44.182

8.  Oxidative Stress in Parkinson's Disease: A Systematic Review and Meta-Analysis.

Authors:  Zexu Wei; Xiaowan Li; Xixi Li; Qingshan Liu; Yong Cheng
Journal:  Front Mol Neurosci       Date:  2018-07-05       Impact factor: 5.639

Review 9.  Parkinson's Disease and the Environment.

Authors:  Nicole Ball; Wei-Peng Teo; Shaneel Chandra; James Chapman
Journal:  Front Neurol       Date:  2019-03-19       Impact factor: 4.003
  9 in total

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