Literature DB >> 3470299

Picogram measurement of prostaglandin E2 synthesis by gastric mucosa by high-performance liquid chromatography.

T A Stein, L Angus, E Borrero, L J Auguste, L Wise.   

Abstract

Prostaglandin biosynthesis by gastric mucosa was determined by a 1-min incubation, solvent extraction, and reaction with panacyl bromide. The prostaglandin ester was measured by normal-phase high-performance liquid chromatography. The prostaglandin E2 levels of normal gastric mucosa of rats and swine were 90.6 +/- 31.0 and 79.8 +/- 39.8 pg/min/mg tissue, respectively. This method was sensitive to 40 pg and specific for prostaglandin E2.

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Year:  1987        PMID: 3470299     DOI: 10.1016/s0021-9673(01)94653-9

Source DB:  PubMed          Journal:  J Chromatogr


  2 in total

1.  The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells.

Authors:  T Yasui; M Akatsuka; K Tobetto; M Hayaishi; T Ando
Journal:  Agents Actions       Date:  1992-09

2.  The effect of cocaine on gastric mucosal PGE(2), LTC(4) and ulcerations.

Authors:  L D Angus; T A Stein; L J Auguste; J Gintautas; J Westervelt; L Wise; G W Shaftan
Journal:  Mediators Inflamm       Date:  1993       Impact factor: 4.711

  2 in total

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