Literature DB >> 34698955

Baseline and Process Factors of Anti-Retroviral Therapy That Predict Loss to Follow-up Among People Living with HIV/AIDS in China: A Retrospective Cohort Study.

Jinzhao Xie1, Jing Gu2,3, Xiuyuan Chen1, Cong Liu4, Haidan Zhong4, Peishan Du4, Quanmin Li4, Joseph T F Lau5, Chun Hao1, Linghua Li6, Yuantao Hao1, Weiping Cai4.   

Abstract

We explored the predictors and predictive models of loss to follow-up (LTFU) during the first year of anti-retroviral therapy (ART). LTFU was defined as the failure to visit the clinic for antiretroviral drugs for ≥ 90 days after the last missed scheduled visit. Based on the electronic medical records of 5953 patients who were HIV positive and began ART between 2016 and 2019 in China, the LTFU rate was 7.24 (95% confidence interval 6.49-7.97) per 100 person-years during the first year of ART. ART baseline factors were associated with LTFU, but were non-optimal predictors. A model including ART process-related factors such as follow-up behaviors and physical health status had an area under the receiver operating characteristic curve of 73.4% for predicting LTFU. Therefore, the medical records of follow-up visits can be used to identify patients with a high risk of LTFU and allow interventions to be implemented proactively.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Antiretroviral therapy; China; Loss to follow-up; Predictive model

Mesh:

Year:  2021        PMID: 34698955     DOI: 10.1007/s10461-021-03466-8

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


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