Miklos Acs1, Sebastian Häusler2, Hamid-Reza Lighvani3, Jozef Zustin4,5, Pompiliu Piso6. 1. Department of General and Visceral Surgery, Krankenhaus Barmherzige Brüder, Regensburg, Germany; miklos.acs@barmherzige-regensburg.de. 2. Department of Obstetrics and Gynecology, Krankenhaus Barmherzige Brüder, Klinik St. Hedwig, Regensburg, Germany. 3. Department of Nuclear Medicine, Krankenhaus Barmherzige Brüder, Regensburg, Germany. 4. Gerhard Domagk Institute of Pathology, University Medical Center Muenster, Muenster, Germany. 5. Institute of Pathology Regensburg, Regensburg, Germany. 6. Department of General and Visceral Surgery, Krankenhaus Barmherzige Brüder, Regensburg, Germany.
Abstract
BACKGROUND/AIM: Malignant struma ovarii is an extremely rare tumor entity among ovarian tumors. In the presence of ascites and peritoneal metastases, the preoperative appearance may resemble the most common epithelial ovarian carcinoma (EOC) and accordingly, the surgical therapy may be identical if a preoperative histology diagnosis is not possible. The objective of this case report is to present a patient with histopathologically confirmed malignant struma ovarii who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS and HIPEC) with the aim of complete tumor resection. CASE REPORT: This study reports on a patient with preoperatively proven peritoneal metastasis of an 18 cm ovarian tumor with large struma ovarii and papillary thyroid carcinoma within the struma, who was treated with CRS and HIPEC after neoadjuvant chemotherapy. CONCLUSION: This disease has a significantly better prognosis than EOC, however, HIPEC could provide an additional effect in examining the presence of peritoneal metastasis.
BACKGROUND/AIM: Malignant struma ovarii is an extremely rare tumor entity among ovarian tumors. In the presence of ascites and peritoneal metastases, the preoperative appearance may resemble the most common epithelial ovarian carcinoma (EOC) and accordingly, the surgical therapy may be identical if a preoperative histology diagnosis is not possible. The objective of this case report is to present a patient with histopathologically confirmed malignant struma ovarii who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS and HIPEC) with the aim of complete tumor resection. CASE REPORT: This study reports on a patient with preoperatively proven peritoneal metastasis of an 18 cm ovarian tumor with large struma ovarii and papillary thyroid carcinoma within the struma, who was treated with CRS and HIPEC after neoadjuvant chemotherapy. CONCLUSION: This disease has a significantly better prognosis than EOC, however, HIPEC could provide an additional effect in examining the presence of peritoneal metastasis.