BACKGROUND/AIM: Current literature reports regarding the effect of lidocaine in laparoscopic colectomies are still inconclusive. The purpose of this study was to review the current literature and estimate the overall effect of intravenous lidocaine administration in postoperative recovery of patients submitted to laparoscopic colectomies. MATERIALS AND METHODS: This study was completed based on the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic screening using scholar databases was performed (Medline, Scopus, Web of Science, CENTRAL). RESULTS: In total, 8 studies and 407 patients were included in this meta-analysis. Introduction of intravenous lidocaine in the perioperative analgesia scheme did not improve hospitalization duration (p=0.23), morphine consumption (p=0.96), perioperative bowel function (first flatus p=0.40, first bowel opened p=0.13, first diet p=0.16), or the overall complication rates (p=0.42). Overall, high heterogeneity levels were identified. CONCLUSION: Current evidence indicates that lidocaine does not improve rehabilitation after laparoscopic colectomies.
BACKGROUND/AIM: Current literature reports regarding the effect of lidocaine in laparoscopic colectomies are still inconclusive. The purpose of this study was to review the current literature and estimate the overall effect of intravenous lidocaine administration in postoperative recovery of patients submitted to laparoscopic colectomies. MATERIALS AND METHODS: This study was completed based on the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic screening using scholar databases was performed (Medline, Scopus, Web of Science, CENTRAL). RESULTS: In total, 8 studies and 407 patients were included in this meta-analysis. Introduction of intravenous lidocaine in the perioperative analgesia scheme did not improve hospitalization duration (p=0.23), morphine consumption (p=0.96), perioperative bowel function (first flatus p=0.40, first bowel opened p=0.13, first diet p=0.16), or the overall complication rates (p=0.42). Overall, high heterogeneity levels were identified. CONCLUSION: Current evidence indicates that lidocaine does not improve rehabilitation after laparoscopic colectomies.
Authors: Nicholas T Ventham; Ewan D Kennedy; Richard R Brady; Hugh M Paterson; Doug Speake; Irwin Foo; Kenneth C H Fearon Journal: World J Surg Date: 2015-09 Impact factor: 3.352
Authors: Abdourahamane Kaba; Stanislas R Laurent; Bernard J Detroz; Daniel I Sessler; Marcel E Durieux; Maurice L Lamy; Jean L Joris Journal: Anesthesiology Date: 2007-01 Impact factor: 7.892
Authors: R Tikuišis; P Miliauskas; N E Samalavičius; A Žurauskas; R Samalavičius; V Zabulis Journal: Tech Coloproctol Date: 2013-09-13 Impact factor: 3.781