Literature DB >> 34696895

Paving the way for designing drugs targeting TMEM16A.

Simone Pifferi1, Anna Menini2.   

Abstract

The calcium-activated chloride channel TMEM16A is involved in several physiological processes and is an important pharmacological target. Dinsdale and colleagues recently unveiled several residues in the outer pore region that constitute a critical site for the design of drugs that modulate TMEM16A channels.
Copyright © 2021 Elsevier Ltd. All rights reserved.

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Year:  2021        PMID: 34696895     DOI: 10.1016/j.tips.2021.10.005

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


  1 in total

1.  Ca2+-Activated Chloride Channels and Phospholipid Scramblases.

Authors:  Simone Pifferi; Anna Boccaccio
Journal:  Int J Mol Sci       Date:  2022-02-15       Impact factor: 5.923

  1 in total

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