Stimuli-Responsive Chiroptical Switching.

"Chirality" governs many fundamental properties in chemistry and biochemistry. While early investigations on stereochemistry are primarily dedicated to static chirality, there is an increasing interest in the field of dynamic chirality (chiral switches). These chiral switches are essential in controlling the directionality in molecular motors. Dynamic chiralities are equally crucial in switchable stereoselectivity, switchable asymmetric catalysis and enantioselective separation. Herein, we limit our discussion to recent advances on stimuli-induced chiroptical switching of axial, helical, and planar chirality in response to external stimuli. We also discuss a few examples of applications of the switchable chirality.