Literature DB >> 3469275

Loss of HLA-A,B,C in colorectal carcinoma is related to the degree of de-differentiation.

F Momburg, P Möller, G Moldenhauer, G J Hämmerling.   

Abstract

By means of immunoperoxidase staining of frozen sections 100 primary colorectal carcinomas and 19 metastases were studied for the expression of HLA-A,B,C antigens. A substantial number of the tumours showed a deficient class I expression. The loss of HLA-A,B,C correlated with the degree of de-differentiation.

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Year:  1986        PMID： 3469275     DOI： 10.1111/j.1744-313x.1986.tb01101.x

Source DB:  PubMed          Journal:  J Immunogenet        ISSN： 0305-1811


  7 in total

1.  Application of isoelectric focusing for studies of major histocompatibility complex class I antigen expression on human carcinomas and sarcomas.

Authors:  P Wang; F Vánky; E Klein
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

2.  Altered growth of a human neuroendocrine carcinoma line after transfection of a major histocompatibility complex class I gene.

Authors:  M E Sunday; K J Isselbacher; S Gattoni-Celli; C G Willett
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

3.  Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT).

Authors:  S Gattoni-Celli; C G Willett; D B Rhoads; B Simon; R M Strauss; K Kirsch; K J Isselbacher
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

4.  Importance of MHC antigen expression on solid tumors in the in vitro interaction with autologous blood lymphocytes.

Authors:  F Vánky; G Stuber; J Willems; K Sjöwall; B Larsson; K Böök; T Ivert; A Péterffy; E Klein
Journal:  Cancer Immunol Immunother       Date:  1988       Impact factor: 6.968

5.  Expression of the adhesion molecule ICAM-1 and major histocompatibility complex class I antigens on human tumor cells is required for their interaction with autologous lymphocytes in vitro.

Authors:  F Vánky; P Wang; M Patarroyo; E Klein
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

6.  Lack of MHC class I antigens and tumour aggressiveness of the squamous cell carcinoma of the larynx.

Authors:  F Esteban; A Concha; M Delgado; M Pérez-Ayala; F Ruiz-Cabello; F Garrido
Journal:  Br J Cancer       Date:  1990-12       Impact factor: 7.640

Review 7.  Tumor microenvironment of adult T-cell leukemia/lymphoma.

Authors:  Mai Takeuchi; Hiroaki Miyoshi; Koichi Ohshima
Journal:  J Clin Exp Hematop       Date:  2021
  7 in total

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