Literature DB >> 34690582

Psychedelics as Reemerging Treatments for Anxiety Disorders: Possibilities and Challenges in a Nascent Field.

Franklin King1, Rebecca Hammond1.   

Abstract

Although psychedelics initially showed promise in treating anxiety disorders, psychedelics were criminalized and research halted in the early 1970s. A subsequent resurgence of research into psychiatric benefits of psychedelic-assisted psychotherapy in the last 20 years has led to a potential paradigm shift in the treatment of numerous psychiatric disorders, including anxiety disorders. Despite accumulating evidence and likely U.S. Food and Drug Administration approval in the next 2-3 years, the emerging field of psychedelic medicine faces several challenges. Obstacles include ongoing barriers on the regulatory level, lack of education, stigma among mental health clinicians, cost and scalability, and a dearth of specialized personnel prepared to provide these treatments. Deeper issues of ethical responsibility and inclusivity also exist given the historical discovery and use of psychedelics by indigenous peoples throughout the world as well the ongoing disparities in mental health delivery and access within psychiatry and psychedelic research.
Copyright © 2021 by the American Psychiatric Association.

Entities:  

Keywords:  Psychedelics and anxiety disorders

Year:  2020        PMID: 34690582      PMCID: PMC8475912          DOI: 10.1176/appi.focus.20200047

Source DB:  PubMed          Journal:  Focus (Am Psychiatr Publ)        ISSN: 1541-4094


  73 in total

1.  Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials.

Authors:  Teri S Krebs; Pål-Ørjan Johansen
Journal:  J Psychopharmacol       Date:  2012-03-08       Impact factor: 4.153

2.  Functional network dysfunction in anxiety and anxiety disorders.

Authors:  C M Sylvester; M Corbetta; M E Raichle; T L Rodebaugh; B L Schlaggar; Y I Sheline; C F Zorumski; E J Lenze
Journal:  Trends Neurosci       Date:  2012-06-02       Impact factor: 13.837

3.  Efficacy and enlightenment: LSD psychotherapy and the Drug Amendments of 1962.

Authors:  Matthew Oram
Journal:  J Hist Med Allied Sci       Date:  2012-08-16       Impact factor: 2.088

4.  Trends in Racial-Ethnic Disparities in Access to Mental Health Care, 2004-2012.

Authors:  Benjamin Lê Cook; Nhi-Ha Trinh; Zhihui Li; Sherry Shu-Yeu Hou; Ana M Progovac
Journal:  Psychiatr Serv       Date:  2016-08-01       Impact factor: 3.084

5.  Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing population.

Authors:  Kim Wolff; E M Tsapakis; A R Winstock; D Hartley; D Holt; M L Forsling; Katherine J Aitchison
Journal:  J Psychopharmacol       Date:  2006-05       Impact factor: 4.153

6.  Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report.

Authors:  Flávia de L Osório; Rafael F Sanches; Ligia R Macedo; Rafael G dos Santos; João P Maia-de-Oliveira; Lauro Wichert-Ana; Draulio B de Araujo; Jordi Riba; José A Crippa; Jaime E Hallak
Journal:  Braz J Psychiatry       Date:  2015 Jan-Mar       Impact factor: 2.697

7.  Comparative efficacy of antidepressants in preventing relapse in anxiety disorders - a meta-analysis.

Authors:  Mary Rocco Donovan; Paul Glue; Sheela Kolluri; Birol Emir
Journal:  J Affect Disord       Date:  2009-07-17       Impact factor: 4.839

8.  Five Facets of Mindfulness and Psychological Health: Evaluating a Psychological Model of the Mechanisms of Mindfulness.

Authors:  David B Brown; Adrian J Bravo; Corey R Roos; Matthew R Pearson
Journal:  Mindfulness (N Y)       Date:  2014-10-28

9.  Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial.

Authors:  Stephen Ross; Anthony Bossis; Jeffrey Guss; Gabrielle Agin-Liebes; Tara Malone; Barry Cohen; Sarah E Mennenga; Alexander Belser; Krystallia Kalliontzi; James Babb; Zhe Su; Patricia Corby; Brian L Schmidt
Journal:  J Psychopharmacol       Date:  2016-12       Impact factor: 4.153

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