| Literature DB >> 34688409 |
Mario Del Rosso1, Gabriella Fibbi2, Anna Laurenzana2, Francesca Margheri2, Anastasia Chillà2.
Abstract
In their new article in the Journal of Investigative Dermatology, Tseng et al. (2021) confirm that the sensitivity of melanoma cells to anti‒PD-L1 checkpoint inhibitor therapy is correlated with high PD-L1 surface expression. By blocking PD-L1 membrane clearing, controlled by LRP1 and PAI-1, the expression of high-cell-surface levels of PD-L1 was maintained.Entities:
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Year: 2021 PMID： 34688409 DOI： 10.1016/j.jid.2021.05.004
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551