Literature DB >> 34678215

Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2021.

Anne F Peery1, Seth D Crockett2, Caitlin C Murphy3, Elizabeth T Jensen4, Hannah P Kim2, Matthew D Egberg2, Jennifer L Lund5, Andrew M Moon2, Virginia Pate5, Edward L Barnes2, Courtney L Schlusser5, Todd H Baron2, Nicholas J Shaheen2, Robert S Sandler2.   

Abstract

BACKGROUND & AIMS: Gastrointestinal diseases account for considerable health care use and expenditures. We estimated the annual burden, costs, and research funding associated with gastrointestinal, liver, and pancreatic diseases in the United States.
METHODS: We generated estimates using data from the National Ambulatory Medical Care Survey; National Hospital Ambulatory Medical Care Survey; Nationwide Emergency Department Sample; National Inpatient Sample; Kids' Inpatient Database; Nationwide Readmissions Database; Surveillance, Epidemiology, and End Results program; National Vital Statistics System; Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research; MarketScan Commercial Claims and Encounters data; MarketScan Medicare Supplemental data; United Network for Organ Sharing registry; Medical Expenditure Panel Survey; and National Institutes of Health (NIH).
RESULTS: Gastrointestinal health care expenditures totaled $119.6 billion in 2018. Annually, there were more than 36.8 million ambulatory visits for gastrointestinal symptoms and 43.4 million ambulatory visits with a primary gastrointestinal diagnosis. Hospitalizations for a principal gastrointestinal diagnosis accounted for more than 3.8 million admissions, with 403,699 readmissions. A total of 22.2 million gastrointestinal endoscopies were performed, and 284,844 new gastrointestinal cancers were diagnosed. Gastrointestinal diseases and cancers caused 255,407 deaths. The NIH supported $3.1 billion (7.5% of the NIH budget) for gastrointestinal research in 2020.
CONCLUSIONS: Gastrointestinal diseases are responsible for millions of health care encounters and hundreds of thousands of deaths that annually costs billions of dollars in the United States. To reduce the high burden of gastrointestinal diseases, focused clinical and public health efforts, supported by additional research funding, are warranted.
Copyright © 2022 AGA Institute. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Digestive System Diseases; Endoscopy; Health Care Costs; Neoplasms

Mesh:

Year:  2021        PMID: 34678215     DOI: 10.1053/j.gastro.2021.10.017

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  21 in total

1.  Trends and Projections in National United States Health Care Spending for Gastrointestinal Malignancies (1996-2030).

Authors:  Igor Stukalin; Newaz Shubidito Ahmed; Adam M Fundytus; Alexander S Qian; Stephanie Coward; Gilaad G Kaplan; Robert J Hilsden; Kelly W Burak; Jeffrey K Lee; Siddharth Singh; Christopher Ma
Journal:  Gastroenterology       Date:  2021-12-16       Impact factor: 22.682

Review 2.  The deleterious effects of smoking on the development and progression of chronic pancreatitis.

Authors:  Samuel Y Han; Darwin L Conwell; Philip T Diaz; Amy Ferketich; Christie Y Jeon; Dhiraj Yadav; Phil A Hart
Journal:  Pancreatology       Date:  2022-08-11       Impact factor: 3.977

Review 3.  Missed diagnosis of cirrhosis in the inpatient setting.

Authors:  Alpesh N Amin; Peter H Nguyen; Elliot B Tapper
Journal:  J Hosp Med       Date:  2022-08       Impact factor: 2.899

4.  The optimal timing of elective surgery in sigmoid diverticular disease: a meta-analysis.

Authors:  Sascha Vaghiri; Dimitrios Prassas; Wolfram Trudo Knoefel; Andreas Krieg
Journal:  Langenbecks Arch Surg       Date:  2022-10-10       Impact factor: 2.895

Review 5.  Should We Use High-Flow Nasal Cannula in Patients Receiving Gastrointestinal Endoscopies? Critical Appraisals through Updated Meta-Analyses with Multiple Methodologies and Depiction of Certainty of Evidence.

Authors:  Chi Chan Lee; Teressa Reanne Ju; Pei Chun Lai; Hsin-Ti Lin; Yen Ta Huang
Journal:  J Clin Med       Date:  2022-07-03       Impact factor: 4.964

6.  Diverticulosis Is Associated With Internal Hemorrhoids on Colonoscopy: Possible Clues to Etiology.

Authors:  J A Sninsky; J Galanko; R S Sandler; Anna F Peery
Journal:  Clin Gastroenterol Hepatol       Date:  2022-02-14       Impact factor: 13.576

7.  Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis.

Authors:  Cristina M Hagen; Eva Roth; Theresia Reding Graf; François Verrey; Rolf Graf; Anurag Gupta; Giovanni Pellegrini; Nadège Poncet; Simone Mafalda Rodrigues Camargo
Journal:  World J Gastroenterol       Date:  2022-03-14       Impact factor: 5.742

8.  Dissecting Intra-Tumoral Changes Following Immune Checkpoint Blockades in Intrahepatic Cholangiocarcinoma via Single-Cell Analysis.

Authors:  Bao-Ye Sun; Cheng Zhou; Ruo-Yu Guan; Gao Liu; Zhang-Fu Yang; Zhu-Tao Wang; Wei Gan; Jian Zhou; Jia Fan; Yong Yi; Shuang-Jian Qiu
Journal:  Front Immunol       Date:  2022-04-26       Impact factor: 8.786

9.  Trends in the Comprehension and Management of Gastrointestinal Tract Disorders.

Authors:  Marilena Durazzo; Arianna Ferro; Sharmila Fagoonee; Rinaldo Pellicano
Journal:  J Clin Med       Date:  2022-03-21       Impact factor: 4.241

Review 10.  Difficult Biliary Stones: A Comprehensive Review of New and Old Lithotripsy Techniques.

Authors:  Edoardo Troncone; Michelangela Mossa; Pasquale De Vico; Giovanni Monteleone; Giovanna Del Vecchio Blanco
Journal:  Medicina (Kaunas)       Date:  2022-01-13       Impact factor: 2.430

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