Literature DB >> 34669624

Skeletal Muscle Nitrate as a Regulator of Systemic Nitric Oxide Homeostasis.

Barbora Piknova1, Alan N Schechter1, Ji Won Park1, Anni Vanhatalo2, Andrew M Jones2.   

Abstract

Nonenzymatic nitric oxide (NO) generation via the reduction of nitrate and nitrite ions, along with remarkably high levels of nitrate ions in skeletal muscle, have been described recently. Skeletal muscle nitrate storage may be critical for maintenance of NO homeostasis in healthy aging, and nitrate supplementation may be useful for the treatment of specific pathophysiologies and for enhancing normal functions.
Copyright © 2022 Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a "work of the United States Government" for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government.

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Year:  2022        PMID: 34669624      PMCID: PMC8677611          DOI: 10.1249/JES.0000000000000272

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN: 0091-6331            Impact factor:   6.230


  96 in total

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5.  Myoglobin desaturation with exercise intensity in human gastrocnemius muscle.

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Review 6.  Nitric oxide synthases: regulation and function.

Authors:  Ulrich Förstermann; William C Sessa
Journal:  Eur Heart J       Date:  2011-09-01       Impact factor: 29.983

7.  A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis.

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Journal:  Nat Chem Biol       Date:  2008-05-30       Impact factor: 15.040

8.  Muscle metabolic and neuromuscular determinants of fatigue during cycling in different exercise intensity domains.

Authors:  Matthew I Black; Andrew M Jones; Jamie R Blackwell; Stephen J Bailey; Lee J Wylie; Sinead T J McDonagh; Christopher Thompson; James Kelly; Paul Sumners; Katya N Mileva; Joanna L Bowtell; Anni Vanhatalo
Journal:  J Appl Physiol (1985)       Date:  2016-12-22

Review 9.  Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence.

Authors:  Lorna C Gee; Amrita Ahluwalia
Journal:  Curr Hypertens Rep       Date:  2016-02       Impact factor: 5.369

10.  Ergogenic Effect of Nitrate Supplementation: A Systematic Review and Meta-analysis.

Authors:  Jonathon W Senefeld; Chad C Wiggins; Riley J Regimbal; Paolo B Dominelli; Sarah E Baker; Michael J Joyner
Journal:  Med Sci Sports Exerc       Date:  2020-10
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  3 in total

1.  Combined Effects of Citrulline Plus Nitrate-Rich Beetroot Extract Co-Supplementation on Maximal and Endurance-Strength and Aerobic Power in Trained Male Triathletes: A Randomized Double-Blind, Placebo-Controlled Trial.

Authors:  José Burgos; Aitor Viribay; Diego Fernández-Lázaro; Julio Calleja-González; Josefa González-Santos; Juan Mielgo-Ayuso
Journal:  Nutrients       Date:  2021-12-23       Impact factor: 5.717

2.  Time course of human skeletal muscle nitrate and nitrite concentration changes following dietary nitrate ingestion.

Authors:  Stefan Kadach; Barbora Piknova; Matthew I Black; Ji Won Park; Lee J Wylie; Zdravko Stoyanov; Samantha M Thomas; Nicholas F McMahon; Anni Vanhatalo; Alan N Schechter; Andrew M Jones
Journal:  Nitric Oxide       Date:  2022-01-13       Impact factor: 4.427

3.  Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude - Further Results From the Xtreme Alps Study.

Authors:  Philip J Hennis; Andrew F Cumpstey; Alasdair F O'Doherty; Bernadette O Fernandez; Edward T Gilbert-Kawai; Kay Mitchell; Helen Moyses; Alexandra Cobb; Paula Meale; Helmut Pöhnl; Monty G Mythen; Michael P W Grocott; Denny Z H Levett; Daniel S Martin; Martin Feelisch
Journal:  Front Physiol       Date:  2022-02-28       Impact factor: 4.755

  3 in total

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