Literature DB >> 3466854

Aberrant breakpoints in chronic myelogenous leukaemia; oncogenes and fragile sites.

J L Huret, J Tanzer, M Henry-Amar.   

Abstract

Three hundred and twenty-five aberrant breakpoints in chronic myelogenous leukaemia (CML) with Philadelphia chromosome variant were reviewed. Eight chromosomal bands (3p21, 6p21, 7p22, 11q13, 12p13, 17p13, 17q21, and 17q25) were found to be highly involved. Apart from 17q25, all these bands correspond to oncogenes sites and/or sites involved as primary breakpoints in cancer.

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Year:  1986        PMID: 3466854     DOI: 10.1007/BF00280504

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  3 in total

1.  Clustering of breakpoints to specific chromosomal regions in human neoplasia. A survey of 5,345 cases.

Authors:  F Mitelman
Journal:  Hereditas       Date:  1986       Impact factor: 3.271

2.  Report of the Committee on Chromosome Rearrangements in Neoplasia and on Fragile Sites.

Authors:  R Berger; C D Bloomfield; G R Sutherland
Journal:  Cytogenet Cell Genet       Date:  1985

3.  Restricted number of chromosomal regions implicated in aetiology of human cancer and leukaemia.

Authors:  F Mitelman
Journal:  Nature       Date:  1984 Jul 26-Aug 1       Impact factor: 49.962

  3 in total
  6 in total

1.  Non-random aberrant breakpoints in chronic myelogenous leukaemia revisited. A call for a collaborative study.

Authors:  J L Huret; J Tanzer
Journal:  Hum Genet       Date:  1989-09       Impact factor: 4.132

2.  Aberrant breakpoints in chronic myelogenous leukemia; oncogenes and fragile sites.

Authors:  M De Braekeleer
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

Review 3.  Complex translocations, simple variant translocations and Ph-negative cases in chronic myelogenous leukaemia.

Authors:  J L Huret
Journal:  Hum Genet       Date:  1990-10       Impact factor: 4.132

4.  ABR, an active BCR-related gene.

Authors:  N Heisterkamp; C Morris; J Groffen
Journal:  Nucleic Acids Res       Date:  1989-11-11       Impact factor: 16.971

5.  BAC CGH-array identified specific small-scale genomic imbalances in diploid DMBA-induced rat mammary tumors.

Authors:  Emma Samuelson; Sara Karlsson; Karolina Partheen; Staffan Nilsson; Claude Szpirer; Afrouz Behboudi
Journal:  BMC Cancer       Date:  2012-08-15       Impact factor: 4.430

6.  Molecular signatures of proliferation and quiescence in hematopoietic stem cells.

Authors:  Teresa A Venezia; Akil A Merchant; Carlos A Ramos; Nathan L Whitehouse; Andrew S Young; Chad A Shaw; Margaret A Goodell
Journal:  PLoS Biol       Date:  2004-09-28       Impact factor: 8.029

  6 in total

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