Literature DB >> 3466852

Assignment of human transcobalamin II (TC2) to chromosome 22 using somatic cell hybrids and monosomic meningioma cells.

F Arwert, H J Porck, M Fràter-Schröder, C Brahe, A Geurts van Kessel, A Westerveld, P Meera Khan, K Zang, R R Frants, H T Kortbeek.   

Abstract

Human transcobalamin II (TC2), a vitamin B12 binding serum protein, is synthesized and secreted into the medium by cells growing in vitro. Mouse-man somatic cell hybrids were analyzed in order to map the locus of TC2. The presence of human TC2 in the culture media was correlated with the results of genetic marker and chromosome analysis of the hybrid cells. Chromosome 22 showed 100% concordancy. However, chromosome 6 (90% concordancy) and chromosome 7 (96% concordancy) were not completely excluded. Meningioma cells obtained from patients heterozygous for TC2 showed a concomitant loss of one chromosome 22 and one of the TC2 alleles, strongly supporting the assignment to chromosome 22.

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Year:  1986        PMID： 3466852     DOI： 10.1007/BF00280489

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  15 in total

1.  Enzyme electrophoresis on cellulose acetate gel: zymogram patterns in mgh-mouse and man--Chinese hamster somatic cell hybrids.

Authors:  P Meera Khan
Journal:  Arch Biochem Biophys       Date:  1971-08       Impact factor: 4.013

2.  Studies on transcobalamin (TC). 1. Detection of TC II isoproteins in human serum.

Authors:  M Fràter-Schröder; W H Hitzig; R Bütler
Journal:  Blood       Date:  1979-02       Impact factor: 22.113

3.  Is the DIA1 locus linked to the P blood group locus?

Authors:  P J McAlpine; H Kaita; M Lewis
Journal:  Cytogenet Cell Genet       Date:  1978

4.  Vitamin B12--binding proteins.

Authors:  E Jacob; S J Baker; V Herbert
Journal:  Physiol Rev       Date:  1980-07       Impact factor: 37.312

5.  Are NORs easily translocated to deleted chromosomes?

Authors:  H Zankl; H Huwer
Journal:  Hum Genet       Date:  1978-06-09       Impact factor: 4.132

6.  Synthesis and secretion of the human vitamin B12-binding protein, transcobalamin II, by cultured skin fibroblasts and by bone marrow cells.

Authors:  M Fràter-Schröder; H J Porck; J Erten; M R Müller; B Steinmann; L Kierat; F Arwert
Journal:  Biochim Biophys Acta       Date:  1985-06-30

7.  A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia.

Authors:  A de Klein; A G van Kessel; G Grosveld; C R Bartram; A Hagemeijer; D Bootsma; N K Spurr; N Heisterkamp; J Groffen; J R Stephenson
Journal:  Nature       Date:  1982-12-23       Impact factor: 49.962

8.  Inheritance and genetic linkage of transcobalamin II.

Authors:  S Y Yang; P Coleman; H D Ochs; B Dupont
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

9.  The analysis of malignancy by cell fusion. VII. Cytogenetic analysis of hybrids between malignant and diploid cells and of tumours derived from them.

Authors:  J Jonasson; S Povey; H Harris
Journal:  J Cell Sci       Date:  1977-04       Impact factor: 5.285

10.  Congenital disorders of vitamin B12 transport and their contributions to concepts. II.

Authors:  C A Hall
Journal:  Yale J Biol Med       Date:  1981 Nov-Dec
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  14 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 11.

Authors:  A M Buchberg; M S Buckwalter; S A Camper
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11.

Authors:  M L Bloom; B K Lee; C S Birkenmeier; Y Ma; W E Zimmer; S R Goodman; E M Eicher; J E Barker
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 4.  Mouse chromosome 11.

Authors:  A M Buchberg; J J Moskow; M S Buckwalter; S A Camper
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 6.  Transcobalamin II deficiency: case report and review of the literature.

Authors:  Y Kaikov; L D Wadsworth; C A Hall; P C Rogers
Journal:  Eur J Pediatr       Date:  1991-10       Impact factor: 3.183

7.  Regional localization and molecular characterization of a DNA sequence on the long arm of chromosome 22.

Authors:  E Göttert; R Metzdorf; U Färber; N Blin
Journal:  Hum Genet       Date:  1989-03       Impact factor: 4.132

Review 8.  Cellular uptake of cobalamin: transcobalamin and the TCblR/CD320 receptor.

Authors:  Edward V Quadros; Jeffrey M Sequeira
Journal:  Biochimie       Date:  2013-02-14       Impact factor: 4.079

9.  Transcobalamin (TC) deficiency--potential cause of bone marrow failure in childhood.

Authors:  C Prasad; D S Rosenblatt; K Corley; A E L Cairney; C A Rupar
Journal:  J Inherit Metab Dis       Date:  2008-10-29       Impact factor: 4.982

10.  The murine leukemia inhibition factor gene (Lif) is located on proximal chromosome 11, not chromosome 13.

Authors:  D Bottorff; J C Stone
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957
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