Literature DB >> 3466694

Idarubicin in advanced breast cancer: a phase II study.

R Lionetto, P Pronzato, P F Conte, M R Sertoli, D Amoroso, R Rosso.   

Abstract

Twenty-nine patients with metastatic breast cancer were treated orally with idarubicin (15 mg/m2 X 3 days every 3-4 weeks). Objective response was seen in 31% of all patients. Toxicity was acceptable. There should be further clinical trials of new anthracycline antibiotic.

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Year:  1986        PMID: 3466694

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  8 in total

Review 1.  Idarubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer.

Authors:  L M Hollingshead; D Faulds
Journal:  Drugs       Date:  1991-10       Impact factor: 9.546

Review 2.  Oral idarubicin. A review of its pharmacological properties and clinical efficacy in the treatment of haematological malignancies and advanced breast cancer.

Authors:  M M Buckley; H M Lamb
Journal:  Drugs Aging       Date:  1997-07       Impact factor: 3.923

3.  Phase II study of 4-demethoxydaunorubicin in previously untreated extensive disease non-small cell lung cancer.

Authors:  T Umsawasdi; T B Felder; D Jeffries; R A Newman
Journal:  Invest New Drugs       Date:  1990       Impact factor: 3.850

4.  Phase I study of idarubicin administered orally on a daily x 3 schedule.

Authors:  D J Stewart; S Verma; J A Maroun; L Robillard; D J Perrault; V Young; S Gupta; B Fontaine
Journal:  Invest New Drugs       Date:  1990-08       Impact factor: 3.850

Review 5.  Oral idarubicin--an anthracycline derivative with unique properties.

Authors:  M Goebel
Journal:  Ann Hematol       Date:  1993-01       Impact factor: 3.673

6.  A phase II study of oral idarubicin (4-demethoxydaunorubicin) in advanced breast cancer.

Authors:  N S Stuart; M H Cullen; T J Priestman; G R Blackledge; C J Tyrrell
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

7.  Combination chemotherapy with 5-fluorouracil, oral Idarubicin, and cyclophosphamide (FIC) in metastatic breast cancer--an open phase II study.

Authors:  K Kolarić; V Potrebica; D Vukas; Z Mechl; B Sopkova
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

Review 8.  Potential role of oral anthracyclines in older patients with cancer.

Authors:  W S Lasota; D L de Valeriola; M J Piccart
Journal:  Drugs Aging       Date:  1994-05       Impact factor: 3.923

  8 in total

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