Literature DB >> 3466674

A unique 8;16 translocation in two infants with poorly differentiated monoblastic leukemia.

R Bernstein, M R Pinto, I Spector, L G Macdougall.   

Abstract

Acute monoblastic leukemia is nonrandomly associated with abnormalities involving 11q. Two infants, one a neonate and the other 19 months of age, had the same hitherto undescribed karyotypic abnormality, t(8;16)(p11;p13), associated with acute nonlymphocytic leukemia M5a. The older child had an additional translocation, t(10;11)(q11;p15), but the chromosome arms affected were the opposite to those described in acute nonlymphocytic leukemia M5a of childhood. Therefore, it is postulated that genes involved in monocytic differentiation may be situated on 8p11 or 16p13, as well as on 11q.

Entities:  

Mesh：

Year:  1987        PMID： 3466674     DOI： 10.1016/0165-4608(87)90101-4

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  4 in total

1.  Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia.

Authors:  T Hanada; I Ono; Y Minosaki; N Moriyama; S Nakahara; A Ohtsu
Journal:  Eur J Pediatr       Date:  1991-03       Impact factor: 3.183

2.  Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

Authors:  Eva A Coenen; C Michel Zwaan; Dirk Reinhardt; Christine J Harrison; Oskar A Haas; Valerie de Haas; Vladimir Mihál; Barbara De Moerloose; Marta Jeison; Jeffrey E Rubnitz; Daisuke Tomizawa; Donna Johnston; Todd A Alonzo; Henrik Hasle; Anne Auvrignon; Michael Dworzak; Andrea Pession; Vincent H J van der Velden; John Swansbury; Kit-fai Wong; Kiminori Terui; Sureyya Savasan; Mark Winstanley; Goda Vaitkeviciene; Martin Zimmermann; Rob Pieters; Marry M van den Heuvel-Eibrink
Journal:  Blood       Date:  2013-08-23       Impact factor: 22.113

3.  Comparison between karyotyping-FISH-reverse transcription PCR and RNA-sequencing-fusion gene identification programs in the detection of KAT6A-CREBBP in acute myeloid leukemia.

Authors:  Ioannis Panagopoulos; Synne Torkildsen; Ludmila Gorunova; Anne Tierens; Geir E Tjønnfjord; Sverre Heim
Journal:  PLoS One       Date:  2014-05-05       Impact factor: 3.240

4.  Isolated granulocytic sarcoma of the nasopharynx: a case report and review of the literature.

Authors:  Prakash Vishnu; Ravindra Reddy Chuda; Dick G Hwang; David M Aboulafia
Journal:  Int Med Case Rep J       Date:  2013-12-17
  4 in total

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