Literature DB >> 34661149

Epigenetic Trajectories of the Premalignant-to-Malignant Transition of Chronic Lymphocytic Leukemia.

Davide Rossi1,2,3.   

Abstract

Kretzmer and colleagues show that the transition to altered methylome occurs very early in chronic lymphocytic leukemia, and once acquired, it is a clonal and extremely stable change. However, the precise time point when the leukemic clone starts deviating significantly from the normal B-cell differentiation trajectory is still elusive. See related article by Kretzmer et al., p. 54. ©2020 American Association for Cancer Research.

Entities:  

Year:  2020        PMID： 34661149      PMCID： PMC8500724          DOI： 10.1158/2643-3230.BCD-20-0207

Source DB:  PubMed          Journal:  Blood Cancer Discov        ISSN： 2643-3230


  10 in total

Review 1.  Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.

Authors:  Nicholas Chiorazzi; Manlio Ferrarini
Journal:  Blood       Date:  2010-12-09       Impact factor: 22.113

Review 2.  Monoclonal B-cell lymphocytosis and early-stage chronic lymphocytic leukemia: diagnosis, natural history, and risk stratification.

Authors:  Paolo Strati; Tait D Shanafelt
Journal:  Blood       Date:  2015-06-11       Impact factor: 22.113

Review 3.  Chronic lymphocytic leukaemia: from genetics to treatment.

Authors:  Francesc Bosch; Riccardo Dalla-Favera
Journal:  Nat Rev Clin Oncol       Date:  2019-11       Impact factor: 66.675

Review 4.  Genetics of MDS.

Authors:  Seishi Ogawa
Journal:  Blood       Date:  2019-01-22       Impact factor: 22.113

5.  DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia.

Authors:  Christopher C Oakes; Marc Seifert; Yassen Assenov; Lei Gu; Martina Przekopowitz; Amy S Ruppert; Qi Wang; Charles D Imbusch; Andrius Serva; Sandra D Koser; David Brocks; Daniel B Lipka; Olga Bogatyrova; Dieter Weichenhan; Benedikt Brors; Laura Rassenti; Thomas J Kipps; Daniel Mertens; Marc Zapatka; Peter Lichter; Hartmut Döhner; Ralf Küppers; Thorsten Zenz; Stephan Stilgenbauer; John C Byrd; Christoph Plass
Journal:  Nat Genet       Date:  2016-01-18       Impact factor: 38.330

6.  The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia.

Authors:  Renée Beekman; Vicente Chapaprieta; Núria Russiñol; Roser Vilarrasa-Blasi; Núria Verdaguer-Dot; Joost H A Martens; Martí Duran-Ferrer; Marta Kulis; François Serra; Biola M Javierre; Steven W Wingett; Guillem Clot; Ana C Queirós; Giancarlo Castellano; Julie Blanc; Marta Gut; Angelika Merkel; Simon Heath; Anna Vlasova; Sebastian Ullrich; Emilio Palumbo; Anna Enjuanes; David Martín-García; Sílvia Beà; Magda Pinyol; Marta Aymerich; Romina Royo; Montserrat Puiggros; David Torrents; Avik Datta; Ernesto Lowy; Myrto Kostadima; Maša Roller; Laura Clarke; Paul Flicek; Xabier Agirre; Felipe Prosper; Tycho Baumann; Julio Delgado; Armando López-Guillermo; Peter Fraser; Marie-Laure Yaspo; Roderic Guigó; Reiner Siebert; Marc A Martí-Renom; Xose S Puente; Carlos López-Otín; Ivo Gut; Hendrik G Stunnenberg; Elias Campo; Jose I Martin-Subero
Journal:  Nat Med       Date:  2018-05-21       Impact factor: 53.440

7.  Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.

Authors:  Anat Biran; Noelia Purroy; Camilla K Lemvigh; Kendell Clement; Michaela Gruber; Catherine J Wu; Alexander Meissner; Helene Kretzmer; Hongcang Gu; Laura Rassenti; Arman W Mohammad; Connie Lesnick; Susan L Slager; Esteban Braggio; Tait D Shanafelt; Neil E Kay; Stacey M Fernandes; Jennifer R Brown; Lili Wang; Shuqiang Li; Kenneth J Livak; Donna S Neuberg; Sven Klages; Bernd Timmermann; Thomas J Kipps; Elias Campo; Andreas Gnirke
Journal:  Blood Cancer Discov       Date:  2020-12-03

8.  Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.

Authors:  Federico Gaiti; Ronan Chaligne; Hongcang Gu; Ryan M Brand; Steven Kothen-Hill; Rafael C Schulman; Kirill Grigorev; Davide Risso; Kyu-Tae Kim; Alessandro Pastore; Kevin Y Huang; Alicia Alonso; Caroline Sheridan; Nathaniel D Omans; Evan Biederstedt; Kendell Clement; Lili Wang; Joshua A Felsenfeld; Erica B Bhavsar; Martin J Aryee; John N Allan; Richard Furman; Andreas Gnirke; Catherine J Wu; Alexander Meissner; Dan A Landau
Journal:  Nature       Date:  2019-05-15       Impact factor: 49.962

9.  The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome.

Authors:  Martí Duran-Ferrer; Guillem Clot; Ferran Nadeu; Renée Beekman; Tycho Baumann; Jessica Nordlund; Yanara Marincevic-Zuniga; Gudmar Lönnerholm; Alfredo Rivas-Delgado; Silvia Martín; Raquel Ordoñez; Giancarlo Castellano; Marta Kulis; Ana C Queirós; Seung-Tae Lee; Joseph Wiemels; Romina Royo; Montserrat Puiggrós; Junyan Lu; Eva Giné; Sílvia Beà; Pedro Jares; Xabier Agirre; Felipe Prosper; Carlos López-Otín; Xosé S Puente; Christopher C Oakes; Thorsten Zenz; Julio Delgado; Armando López-Guillermo; Elías Campo; José Ignacio Martín-Subero
Journal:  Nat Cancer       Date:  2020-11-02

10.  Cellular origin and pathophysiology of chronic lymphocytic leukemia.

Authors:  Marc Seifert; Ludger Sellmann; Johannes Bloehdorn; Frederik Wein; Stephan Stilgenbauer; Jan Dürig; Ralf Küppers
Journal:  J Exp Med       Date:  2012-10-22       Impact factor: 14.307
  10 in total

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