Literature DB >> 34661140

The Genomic Landscape of HIV-Associated Plasmablastic Lymphoma.

Ralf Küppers1.   

Abstract

A combined whole-exome and targeted sequencing study of 110 cases of human immunodeficiency virus-associated plasmablastic lymphomas revealed a distinct landscape of genetic lesions for this lymphoma entity, including a particular role of mutations in STAT3 and other members of the JAK-STAT signaling pathway, and of the RAS family in its pathogenesis. See related article by Liu et al., p. 112. ©2020 American Association for Cancer Research.

Entities:  

Mesh：

Year:  2020        PMID： 34661140      PMCID： PMC8500707          DOI： 10.1158/2643-3249.BCD-20-0075

Source DB:  PubMed          Journal:  Blood Cancer Discov        ISSN： 2643-3230


  10 in total

1.  Gene expression analysis of plasmablastic lymphoma identifies downregulation of B-cell receptor signaling and additional unique transcriptional programs.

Authors:  J Chapman; A J Gentles; V Sujoy; F Vega; C I Dumur; T L Blevins; L Bernal-Mizrachi; M Mosunjac; A Pimentel; D Zhu; I S Lossos
Journal:  Leukemia       Date:  2015-04-24       Impact factor: 11.528

Review 2.  The biology and treatment of plasmablastic lymphoma.

Authors:  Jorge J Castillo; Michele Bibas; Roberto N Miranda
Journal:  Blood       Date:  2015-01-30       Impact factor: 22.113

3.  Plasmablastic lymphoma phenotype is determined by genetic alterations in MYC and PRDM1.

Authors:  Santiago Montes-Moreno; Nerea Martinez-Magunacelaya; Tomás Zecchini-Barrese; Sonia Gonzalez de Villambrosía; Emma Linares; Tamara Ranchal; María Rodriguez-Pinilla; Ana Batlle; Laura Cereceda-Company; Jose Bernardo Revert-Arce; Carmen Almaraz; Miguel A Piris
Journal:  Mod Pathol       Date:  2016-09-30       Impact factor: 7.842

Review 4.  Mechanisms of B-cell lymphoma pathogenesis.

Authors:  Ralf Küppers
Journal:  Nat Rev Cancer       Date:  2005-04       Impact factor: 60.716

5.  Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion.

Authors:  Kirsty Wienand; Bjoern Chapuy; Chip Stewart; Andrew J Dunford; David Wu; Jaegil Kim; Atanas Kamburov; Timothy R Wood; Fathima Zumla Cader; Matthew D Ducar; Aaron R Thorner; Anwesha Nag; Alexander T Heubeck; Michael J Buonopane; Robert A Redd; Kamil Bojarczuk; Lee N Lawton; Philippe Armand; Scott J Rodig; Jonathan R Fromm; Gad Getz; Margaret A Shipp
Journal:  Blood Adv       Date:  2019-12-10

6.  Plasmablastic lymphomas of the oral cavity: a new entity associated with the human immunodeficiency virus infection.

Authors:  H J Delecluse; I Anagnostopoulos; F Dallenbach; M Hummel; T Marafioti; U Schneider; D Huhn; A Schmidt-Westhausen; P A Reichart; U Gross; H Stein
Journal:  Blood       Date:  1997-02-15       Impact factor: 22.113

Review 7.  A lymphomagenic role for HIV beyond immune suppression?

Authors:  Riccardo Dolcetti; Annunziata Gloghini; Arnaldo Caruso; Antonino Carbone
Journal:  Blood       Date:  2016-01-14       Impact factor: 22.113

Review 8.  B cells under influence: transformation of B cells by Epstein-Barr virus.

Authors:  Ralf Küppers
Journal:  Nat Rev Immunol       Date:  2003-10       Impact factor: 53.106

9.  Genomic characterization of HIV-associated plasmablastic lymphoma identifies pervasive mutations in the JAK-STAT pathway.

Authors:  Laura Pasqualucci; Raul Rabadan; Pascale Willem; Zhaoqi Liu; Ioan Filip; Karen Gomez; Dewaldt Engelbrecht; Shabnum Meer; Pooja N Lalloo; Pareen Patel; Yvonne Perner; Junfei Zhao; Jiguang Wang
Journal:  Blood Cancer Discov       Date:  2020-07

10.  Genetic lesions in MYC and STAT3 drive oncogenic transcription factor overexpression in plasmablastic lymphoma.

Authors:  Julia Garcia-Reyero; Nerea Martinez Magunacelaya; Sonia Gonzalez de Villambrosia; Sanam Loghavi; Angela Gomez Mediavilla; Raul Tonda; Sergi Beltran; Marta Gut; Ainara Pereña Gonzalez; Emanuele d'Ámore; Carlo Visco; Joseph D Khoury; Santiago Montes-Moreno
Journal:  Haematologica       Date:  2021-04-01       Impact factor: 9.941
  10 in total
  1 in total

Review 1.  Plasmablastic lymphoma: An update.

Authors:  Jenique Bailly; Nicholas Jenkins; Dharshnee Chetty; Zainab Mohamed; Estelle R Verburgh; Jessica J Opie
Journal:  Int J Lab Hematol       Date:  2022-09       Impact factor: 3.450
  1 in total

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