| Literature DB >> 3465677 |
L Romitti, R P Revoltella, E Vigneti, G Simoni.
Abstract
Serial chromosome studies were performed on four monocytic cell lines established from bone marrow samples of patients suffering from hematopoietic disorders other than leukemia. A spontaneous in vitro transformation towards a malignant phenotype has been found to be related to the karyotype evolution. The correlation between the chromosome changes of these cell lines and those described in human cancer and leukemia is discussed.Entities:
Mesh:
Year: 1986 PMID: 3465677 DOI: 10.1007/BF00282544
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132