Literature DB >> 346558

Role of glutathione in reversing the deleterious effects of a thiol-oxidizing agent in Escherichia coli.

K A Hibberd, P B Berget, H R Warner, J A Fuchs.   

Abstract

Diamide was found to be much less specific for the oxidation of glutathione in vivo in Escherichia coli than had been previously assumed. In vivo, only a slight alteration of the ratio of reduced to oxidized glutathione was found, whereas a significant amount of glutathione was found in the form of mixed disulfide with proteins. This latter occurrence was postulated as being responsible for the bacteriostatic effect of diamide.

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Year:  1978        PMID： 346558      PMCID： PMC222146          DOI： 10.1128/jb.133.3.1150-1155.1978

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  7 in total

1.  ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES.V. PURIFICATION AND PROPERTIES OF THIOREDOXIN REDUCTASE FROM ESCHERICHIA COLI B.

Authors:  E C MOORE; P REICHARD; L THELANDER
Journal:  J Biol Chem       Date:  1964-10       Impact factor: 5.157

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Mutants of Escherichia coli requiring methionine or vitamin B12.

Authors:  B D DAVIS; E S MINGIOLI
Journal:  J Bacteriol       Date:  1950-07       Impact factor: 3.490

4.  Effect of the thiol-oxidizing agent diamide on the growth of Escherichia coli.

Authors:  R Wax; E Rosenberg; N S Kosower; E M Kosower
Journal:  J Bacteriol       Date:  1970-03       Impact factor: 3.490

5.  Diamide, a new reagent for the intracellular oxidation of glutathione to the disulfide.

Authors:  N S Kosower; E M Kosower; B Wertheim; W S Correa
Journal:  Biochem Biophys Res Commun       Date:  1969-11-06       Impact factor: 3.575

6.  Isolation and initial characterization of glutathione-deficient mutants of Escherichia coli K 12.

Authors:  P Apontoweil; W Berends
Journal:  Biochim Biophys Acta       Date:  1975-07-14

7.  Isolation of an Escherichia coli mutant deficient in glutathione synthesis.

Authors:  J A Fuchs; H R Warner
Journal:  J Bacteriol       Date:  1975-10       Impact factor: 3.490
  7 in total
  2 in total

1.  Redox interconversion of Escherichia coli glutathione reductase. A study with permeabilized and intact cells.

Authors:  A M Mata; M C Pinto; J López-Barea
Journal:  Mol Cell Biochem       Date:  1985-10       Impact factor: 3.396

2.  Glutathione reductase is not required for maintenance of reduced glutathione in Escherichia coli K-12.

Authors:  C K Tuggle; J A Fuchs
Journal:  J Bacteriol       Date:  1985-04       Impact factor: 3.490
  2 in total

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