Literature DB >> 34653875

Apolipoprotein E ε4 is not associated with cognitive impairment in patients with idiopathic REM sleep behavior disorder.

Jun-Sang Sunwoo1, Jung-Ick Byun2, Jin-Sun Jun3, Tae-Joon Kim4, Jung-Won Shin5, Han-Joon Kim6, Ki-Young Jung7.   

Abstract

We analyzed 136 patients (age, 67.5 ± 6.9 years; men, 59.6%) with idiopathic rapid eye movement sleep behavior disorder (iRBD). The results of the neuropsychological tests were not significantly different between APOE ε4 carriers and noncarriers, suggesting that the APOE ε4 allele was not associated with cognitive impairment in iRBD.
Copyright © 2021 Elsevier Ltd. All rights reserved.

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Keywords:  Apolipoprotein E4; Cognitive impairment; REM sleep Behavior disorder; Synucleinopathy

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Year:  2021        PMID: 34653875     DOI: 10.1016/j.parkreldis.2021.10.002

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN: 1353-8020            Impact factor:   4.891


  1 in total

1.  The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia.

Authors:  Jinghuan Gan; Zhichao Chen; Shuai Liu; Zhihong Shi; Yiming Liu; Xiao-Dan Wang; Chunyan Liu; Yong Ji
Journal:  BMC Neurol       Date:  2022-09-19       Impact factor: 2.903

  1 in total

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