Literature DB >> 34647258

Blueprints for Constructing Microgravity Analogs.

Karl H Hasenstein1.   

Abstract

The desire to understand gravitational effects on living things requires the removal of the very factor that determines life on Earth. Unfortunately, the required free-fall conditions that provide such conditions are limited to a few seconds unless earth-orbiting platforms are available. Therefore, attempts have been made to create conditions that simulate reduced gravity or gravity-free conditions ever since the gravity effects have been studied. Such conditions depend mostly on rotating devices (aka clinostats) that alter the gravity vector faster than the biological response time or create conditions that compensate sedimentation by fluid dynamics. Although several sophisticated, commercial instruments are available, they are unaffordable to most individual investigators. This article describes important considerations for the design and construction of low cost but versatile instruments that are sturdy, fully programmable, and affordable. The chapter focuses on detailed construction, programming of microcontrollers, versatility, and reliability of the instrument.
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  3D printing; Accelerometer; Clinostat; LED illumination; Microcontroller programming; Random positioning machine; STL files

Mesh:

Year:  2022        PMID: 34647258     DOI: 10.1007/978-1-0716-1677-2_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  1 in total

1.  Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity.

Authors:  Caizhi Liu; Guohui Zhong; Yuezhang Zhou; Yuchen Yang; Yingjun Tan; Yuheng Li; Xingcheng Gao; Weijia Sun; Jianwei Li; Xiaoyan Jin; Dengchao Cao; Xinxin Yuan; Zizhong Liu; Shuai Liang; Youyou Li; Ruikai Du; Yinlong Zhao; Jianqi Xue; Dingsheng Zhao; Jinping Song; Shukuan Ling; Yingxian Li
Journal:  Cell Prolif       Date:  2020-02-26       Impact factor: 6.831

  1 in total

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