Jacqueline R Lim1, Timothy C Nielsen2, Russell C Dale2, Hannah F Jones2, Amanda Beech3, Natasha Nassar2, Samantha J Lain2, Antonia Shand2,4. 1. Sydney Medical School, The University of Sydney, Sydney, Australia. 2. Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. 3. Department of Endocrinology/Obstetric Medicine, Royal Hospital for Women, Sydney, Australia. 4. Department of Maternal Fetal Medicine, Royal Hospital for Women, Sydney, Australia.
Abstract
BACKGROUND: Autoimmune conditions are associated with adverse pregnancy and offspring outcomes; however, the prevalence in pregnant women is not well understood. Estimates based on administrative data alone may underestimate prevalence. METHODS: A cross-sectional survey of women attending a tertiary referral hospital for antenatal care in December 2018-February 2019 and review of the hospital's maternity database of women giving birth from October 2017-June 2018 to estimate autoimmune disease prevalence. RESULTS: A total of 400 women completed surveys (78% response rate) and 41 (10.3%) reported an autoimmune disease, most commonly Hashimoto's thyroiditis (2.8%) and psoriasis (2.5%). From the maternity database, 112 of 2756 women giving birth (4.1%) had a recorded autoimmune disease, most commonly Hashimoto's thyroiditis (1.3%) followed by coeliac disease, Graves' disease, and immune thrombocytopenic purpura (all 0.4%). CONCLUSION: Autoimmune disease prevalence in pregnant women is higher when self-reported and may be more common than previously reported using administrative data.
BACKGROUND: Autoimmune conditions are associated with adverse pregnancy and offspring outcomes; however, the prevalence in pregnant women is not well understood. Estimates based on administrative data alone may underestimate prevalence. METHODS: A cross-sectional survey of women attending a tertiary referral hospital for antenatal care in December 2018-February 2019 and review of the hospital's maternity database of women giving birth from October 2017-June 2018 to estimate autoimmune disease prevalence. RESULTS: A total of 400 women completed surveys (78% response rate) and 41 (10.3%) reported an autoimmune disease, most commonly Hashimoto's thyroiditis (2.8%) and psoriasis (2.5%). From the maternity database, 112 of 2756 women giving birth (4.1%) had a recorded autoimmune disease, most commonly Hashimoto's thyroiditis (1.3%) followed by coeliac disease, Graves' disease, and immune thrombocytopenic purpura (all 0.4%). CONCLUSION: Autoimmune disease prevalence in pregnant women is higher when self-reported and may be more common than previously reported using administrative data.
Authors: Julia F Simard; Christopher Sjöwall; Lars Rönnblom; Andreas Jönsen; Elisabet Svenungsson Journal: Arthritis Care Res (Hoboken) Date: 2014-11 Impact factor: 4.794
Authors: Julia A O'Rourke; Caitlin Ravichandran; Yamini J Howe; Jennifer E Mullett; Christopher J Keary; Sara B Golas; Amrita R Hureau; Morgan McCormick; Jeanhee Chung; Noel R Rose; Christopher J McDougle Journal: PLoS One Date: 2019-05-29 Impact factor: 3.240