Literature DB >> 34644614

How orthopedic surgeons view open label placebo pills: Ethical and effective, but opposed to personal use.

Michael H Bernstein1, Maayan Rosenfield2, Nathaniel Fuchs2, Molly Magill2, Charlotte R Blease3, Francesca L Beaudoin4, Josiah D Rich5, Karolina Wartolowska6, Richard M Terek7.   

Abstract

OBJECTIVE: To examine attitudes of Open Label Placebos (OLP) among a national sample of US orthopedic surgeons.
METHODS: Orthopedic surgeons across the US were invited to participate in a brief online cross-sectional survey; n = 687 participated. The survey included a short vignette of a surgeon using adjunctive OLPs in addition to opioids for postoperative pain management. Participants indicated how ethical and effective they thought OLPs would be in this context, and whether they would personally consider using OLPs.
RESULTS: Nearly three-quarters (73.9%) of the surgeons considered OLPs ethical. In total, 55.4% and 48.8% of participants said that OLPs would "probably" or "definitely" be effective for Vicodin reduction and pain relief, respectively. However, only 19.2% of participants indicated they were personally willing to consider OLPs, and 59.6% were unwilling to do so.
CONCLUSIONS: Generally, orthopedic surgeons perceive OLPs as both ethical and effective, but would not consider using them in their practice. Further research is needed to identify clinician barriers to OLP use.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Open label placebo; Opioid; Pain; Pain reduction; Placebo

Mesh:

Substances:

Year:  2021        PMID: 34644614      PMCID: PMC8633179          DOI: 10.1016/j.jpsychores.2021.110638

Source DB:  PubMed          Journal:  J Psychosom Res        ISSN: 0022-3999            Impact factor:   3.006


  21 in total

Review 1.  Opioid Abuse in Chronic Pain--Misconceptions and Mitigation Strategies.

Authors:  Nora D Volkow; A Thomas McLellan
Journal:  N Engl J Med       Date:  2016-03-31       Impact factor: 91.245

Review 2.  Sham Surgery in Orthopedics: A Systematic Review of the Literature.

Authors:  Adriaan Louw; Ina Diener; César Fernández-de-Las-Peñas; Emilio J Puentedura
Journal:  Pain Med       Date:  2017-04-01       Impact factor: 3.750

3.  Conditioned open-label placebo for opioid reduction after spine surgery: a randomized controlled trial.

Authors:  Kelsey M Flowers; Megan E Patton; Valerie J Hruschak; Kara G Fields; Emily Schwartz; Jose Zeballos; James D Kang; Rob R Edwards; Ted J Kaptchuk; Kristin L Schreiber
Journal:  Pain       Date:  2021-06-01       Impact factor: 6.961

4.  Open-label placebo clinical trials: is it the rationale, the interaction or the pill?

Authors:  Charlotte R Blease; Michael H Bernstein; Cosima Locher
Journal:  BMJ Evid Based Med       Date:  2019-06-26

5.  Conditioning open-label placebo: a pilot pharmacobehavioral approach for opioid dose reduction and pain control.

Authors:  Leon Morales-Quezada; Ines Mesia-Toledo; Anayali Estudillo-Guerra; Kevin C O'Connor; Jeffrey C Schneider; Douglas J Sohn; David M Crandell; Ted Kaptchuk; Ross Zafonte
Journal:  Pain Rep       Date:  2020-07-20

6.  Effects of open-label placebo on pain, functional disability, and spine mobility in patients with chronic back pain: a randomized controlled trial.

Authors:  Julian Kleine-Borgmann; Katharina Schmidt; Andreas Hellmann; Ulrike Bingel
Journal:  Pain       Date:  2019-12       Impact factor: 6.961

7.  Deceptive and Nondeceptive Placebos to Reduce Pain: An Experimental Study in Healthy Individuals.

Authors:  Tobias Kube; Winfried Rief; Maj-Britt Vivell; N Leonora Schäfer; Teresa Vermillion; Karoline Körfer; Julia A Glombiewski
Journal:  Clin J Pain       Date:  2020-02       Impact factor: 3.442

8.  Treating Pain With Open-Label Placebos: A Qualitative Study With Post-Surgical Pain Patients.

Authors:  Michael H Bernstein; Nathaniel Fuchs; Maayan Rosenfield; Arnold-Peter Weiss; Charlotte Blease; Cosima Locher; Molly Magill; Josiah Rich; Francesca L Beaudoin
Journal:  J Pain       Date:  2021-05-15       Impact factor: 5.820

9.  A survey on beliefs and attitudes of trainee surgeons towards placebo.

Authors:  Mathew J Baldwin; Karolina Wartolowska; Andrew J Carr
Journal:  BMC Surg       Date:  2016-04-27       Impact factor: 2.102

10.  Open-label placebo treatment in chronic low back pain: a randomized controlled trial.

Authors:  Cláudia Carvalho; Joaquim Machado Caetano; Lidia Cunha; Paula Rebouta; Ted J Kaptchuk; Irving Kirsch
Journal:  Pain       Date:  2016-12       Impact factor: 7.926

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