Literature DB >> 34643909

Detection of Mycolactone by Thin Layer Chromatography.

Richard Kwamla Amewu1, Thomas Spangenberg2.   

Abstract

By means of thin layer chromatography coupled to a fluorescence enhancer, a highly sensitive and operationally simple method to detect the mycolactones stemming from the human pathogen Mycobacterium ulcerans was developed and applied to various sample sources.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Boronic acid; Fluorescence; Mycobacterium ulcerans; Mycolactone; Thin layer chromatography; UV-A

Mesh：

Substances：

Year:  2022        PMID： 34643909     DOI： 10.1007/978-1-0716-1779-3_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  8 in total

1.  Relative stereochemical determination and synthesis of the C1-C17 fragment of a new natural polyketide.

Authors:  Etienne Fleury; Marie-Isabelle Lannou; Olivia Bistri; François Sautel; Georges Massiot; Ange Pancrazi; Janick Ardisson
Journal:  J Org Chem       Date:  2009-09-18       Impact factor: 4.354

Review 2.  History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease).

Authors:  Anne-Caroline Chany; Cédric Tresse; Virginie Casarotto; Nicolas Blanchard
Journal:  Nat Prod Rep       Date:  2013-12       Impact factor: 13.423

Review 3.  Structures and mechanisms of polyketide synthases.

Authors:  Chaitan Khosla
Journal:  J Org Chem       Date:  2009-09-04       Impact factor: 4.354

4.  Photodegradation of the Mycobacterium ulcerans toxin, mycolactones: considerations for handling and storage.

Authors:  Estelle Marion; Soizic Prado; Camille Cano; Jérémie Babonneau; Sarah Ghamrawi; Laurent Marsollier
Journal:  PLoS One       Date:  2012-04-13       Impact factor: 3.240

5.  Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease.

Authors:  Paul J Converse; Yalan Xing; Ki Hyun Kim; Sandeep Tyagi; Si-Yang Li; Deepak V Almeida; Eric L Nuermberger; Jacques H Grosset; Yoshito Kishi
Journal:  PLoS Negl Trop Dis       Date:  2014-01-02

6.  Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.

Authors:  Sacha J Pidot; Hui Hong; Torsten Seemann; Jessica L Porter; Marcus J Yip; Artem Men; Matthew Johnson; Peter Wilson; John K Davies; Peter F Leadlay; Timothy P Stinear
Journal:  BMC Genomics       Date:  2008-10-07       Impact factor: 3.969

7.  Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue.

Authors:  Fred Stephen Sarfo; Richard O Phillips; Brian Rangers; Engy A Mahrous; Richard E Lee; Edward Tarelli; Kingsley B Asiedu; Pamela L Small; Mark H Wansbrough-Jones
Journal:  PLoS Negl Trop Dis       Date:  2010-01-05

8.  Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease.

Authors:  Fred S Sarfo; Richard O Phillips; Jihui Zhang; Mohammed K Abass; Justice Abotsi; Yaw A Amoako; Yaw Adu-Sarkodie; Clive Robinson; Mark H Wansbrough-Jones
Journal:  BMC Infect Dis       Date:  2014-04-15       Impact factor: 3.090
  8 in total

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