Literature DB >> 34642166

Failing the frail: The need to broaden the COVID-19 case definition for geriatric patients.

Clare Hunt1,2, Flora Olcott3,2, George Williams4, Terrence Chan3.   

Abstract

The older population has a high mortality with COVID-19 and this cohort often presents atypically with infection. This study compares presenting complaints and observations of older patients with COVID-19 against the established case definition to determine whether the case definition should be broadened to better identify SARS-CoV-2 infection in this age group.This retrospective observational study analysed the presenting complaints and observations of people aged 70 years and over who were admitted to a district general hospital with confirmed SARS-CoV-2 infection from March to May 2020.Out of 225 patients, only 11.5% presented with the trio of cough, fever and breathlessness; 30.2% did not present with any of these symptoms (p<0.001). The most frequent atypical complaints were delirium (25%), general malaise (20%) and falls (19%). Only 32.4% recorded a temperature ≥37.6°C on admission while 20.4% were hypothermic with a temperature <36.4°C (p=0.0003).A significant proportion of older patients with COVID-19 presented with non-specific symptoms and observations. The high proportion of falls and delirium emphasises the need for early geriatrician input, awareness of COVID-19 as a differential for confusion in older patients and to include falls in the case definition for COVID-19 in the older population. © Royal College of Physicians 2021. All rights reserved.

Entities:  

Keywords:  COVID-19; delirium; falls; geriatric medicine; presenting complaints

Mesh:

Year:  2021        PMID: 34642166      PMCID: PMC8806293          DOI: 10.7861/clinmed.2021-0308

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  10 in total

1.  Elderly patients with an atypical presentation of illness in the emergency department.

Authors:  M R Hofman; F van den Hanenberg; I N Sierevelt; C R Tulner
Journal:  Neth J Med       Date:  2017-07       Impact factor: 1.422

2.  Prevalence and prognostic value of Delirium as the initial presentation of COVID-19 in the elderly with dementia: An Italian retrospective study.

Authors:  Tino Emanuele Poloni; Arenn Faye Carlos; Marco Cairati; Chiara Cutaia; Valentina Medici; Eleonora Marelli; Danila Ferrari; Alberto Galli; Paola Bognetti; Annalisa Davin; Alice Cirrincione; Arcangelo Ceretti; Cristina Cereda; Mauro Ceroni; Livio Tronconi; Silvia Vitali; Antonio Guaita
Journal:  EClinicalMedicine       Date:  2020-07-30

3.  Age-related differences in symptoms, diagnosis and prognosis of bacteremia.

Authors:  Astrid L Wester; Oona Dunlop; Kjetil K Melby; Ulf R Dahle; Torgeir Bruun Wyller
Journal:  BMC Infect Dis       Date:  2013-07-24       Impact factor: 3.090

4.  Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study.

Authors:  Annemarie B Docherty; Ewen M Harrison; Christopher A Green; Hayley E Hardwick; Riinu Pius; Lisa Norman; Karl A Holden; Jonathan M Read; Frank Dondelinger; Gail Carson; Laura Merson; James Lee; Daniel Plotkin; Louise Sigfrid; Sophie Halpin; Clare Jackson; Carrol Gamble; Peter W Horby; Jonathan S Nguyen-Van-Tam; Antonia Ho; Clark D Russell; Jake Dunning; Peter Jm Openshaw; J Kenneth Baillie; Malcolm G Semple
Journal:  BMJ       Date:  2020-05-22

5.  Assessing the age specificity of infection fatality rates for COVID-19: systematic review, meta-analysis, and public policy implications.

Authors:  Andrew T Levin; William P Hanage; Nana Owusu-Boaitey; Kensington B Cochran; Seamus P Walsh; Gideon Meyerowitz-Katz
Journal:  Eur J Epidemiol       Date:  2020-12-08       Impact factor: 8.082

6.  Prevalence, incidence and mortality of delirium in patients with COVID-19: a systematic review and meta-analysis.

Authors:  Shih-Chieh Shao; Chien-Cheng Lai; Yi-Hung Chen; Yung-Chang Chen; Ming-Jui Hung; Shu-Chen Liao
Journal:  Age Ageing       Date:  2021-09-11       Impact factor: 10.668

7.  Atypical symptoms, SARS-CoV-2 test results and immunisation rates in 456 residents from eight nursing homes facing a COVID-19 outbreak.

Authors:  Hubert Blain; Lucie Gamon; Edouard Tuaillon; Amandine Pisoni; Nadia Giacosa; Mylène Albrand; Stéphanie Miot; Yves Rolland; Marie-Christine Picot; Jean Bousquet
Journal:  Age Ageing       Date:  2021-05-05       Impact factor: 10.668

8.  Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis.

Authors:  Zhaohai Zheng; Fang Peng; Buyun Xu; Jingjing Zhao; Huahua Liu; Jiahao Peng; Qingsong Li; Chongfu Jiang; Yan Zhou; Shuqing Liu; Chunji Ye; Peng Zhang; Yangbo Xing; Hangyuan Guo; Weiliang Tang
Journal:  J Infect       Date:  2020-04-23       Impact factor: 6.072

9.  Dyspnea rather than fever is a risk factor for predicting mortality in patients with COVID-19.

Authors:  Li Shi; Ying Wang; Yadong Wang; Guangcai Duan; Haiyan Yang
Journal:  J Infect       Date:  2020-05-15       Impact factor: 6.072

10.  Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults.

Authors:  Maria Beatrice Zazzara; Rose S Penfold; Amy L Roberts; Karla A Lee; Hannah Dooley; Carole H Sudre; Carly Welch; Ruth C E Bowyer; Alessia Visconti; Massimo Mangino; Maxim B Freidin; Julia S El-Sayed Moustafa; Kerrin S Small; Benjamin Murray; Marc Modat; Mark S Graham; Jonathan Wolf; Sebastien Ourselin; Finbarr C Martin; Claire J Steves; Mary Ni Lochlainn
Journal:  Age Ageing       Date:  2021-01-08       Impact factor: 10.668

  10 in total

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