Kelly R Morton1, Jerry W Lee2, Rhonda Spencer-Hwang2. 1. Department of Family Medicine, Department of Psychology, Loma Linda University, USA. Electronic address: kmorton@llu.edu. 2. School of Public Health, Loma Linda University, USA.
Abstract
BACKGROUND: Adverse Childhood Experiences (ACEs) consistently predict poor mental and physical health as well as early all-cause mortality. Much work examines health harming behaviors that may be used to cope with ACEs associated stress responses and dysregulation. Limited research has been conducted assessing plant-based dietary intake on the ACEs and mortality relationship. We investigate moderators of the ACEs and mortality association including plant-based dietary intake. OBJECTIVE: The purpose of this study is to examine if the association between ACEs and early mortality is potentially moderated by plant-based dietary intake. PARTICIPANTS: An observational, prospective cohort study that included 9301 Seventh-day Adventists were assessed from 2006 to 2017 in the Biopsychosocial Religion and Health Study (BRHS). METHODS: We examined the potential impact of plant-based intake frequency on the ACEs and all-cause mortality relationship, while adjusting for potential confounders (e.g., demographics, health risks, mental and physical health) in a cox regression survival analysis. RESULTS: ACEs were adversely associated with survival time (HR = 2.76, 95% CI: 1.15-6.64). Plant-based intake was associated with a reduction in the association of 4+ ACEs with early mortality (HR = 0.73, 95% CI: 0.59-0.90) above and beyond demographics, animal-based intake, physical health, mental health, BMI, exercise, and worship. We estimate that after 4+ ACEs, those eating high versus low plant-based dietary intake may live 5.4 years longer. CONCLUSION: Plant-based dietary intake may potentially moderate the ACEs and early mortality relationship; however, observational studies cannot determine causality.
BACKGROUND: Adverse Childhood Experiences (ACEs) consistently predict poor mental and physical health as well as early all-cause mortality. Much work examines health harming behaviors that may be used to cope with ACEs associated stress responses and dysregulation. Limited research has been conducted assessing plant-based dietary intake on the ACEs and mortality relationship. We investigate moderators of the ACEs and mortality association including plant-based dietary intake. OBJECTIVE: The purpose of this study is to examine if the association between ACEs and early mortality is potentially moderated by plant-based dietary intake. PARTICIPANTS: An observational, prospective cohort study that included 9301 Seventh-day Adventists were assessed from 2006 to 2017 in the Biopsychosocial Religion and Health Study (BRHS). METHODS: We examined the potential impact of plant-based intake frequency on the ACEs and all-cause mortality relationship, while adjusting for potential confounders (e.g., demographics, health risks, mental and physical health) in a cox regression survival analysis. RESULTS: ACEs were adversely associated with survival time (HR = 2.76, 95% CI: 1.15-6.64). Plant-based intake was associated with a reduction in the association of 4+ ACEs with early mortality (HR = 0.73, 95% CI: 0.59-0.90) above and beyond demographics, animal-based intake, physical health, mental health, BMI, exercise, and worship. We estimate that after 4+ ACEs, those eating high versus low plant-based dietary intake may live 5.4 years longer. CONCLUSION: Plant-based dietary intake may potentially moderate the ACEs and early mortality relationship; however, observational studies cannot determine causality.
Authors: Robert A Hummer; Christopher G Ellison; Richard G Rogers; Benjamin E Moulton; Ron R Romero Journal: South Med J Date: 2004-12 Impact factor: 0.954
Authors: Jerry W Lee; Kelly R Morton; James Walters; Denise L Bellinger; Terry L Butler; Colwick Wilson; Eric Walsh; Christopher G Ellison; Monica M McKenzie; Gary E Fraser Journal: Int J Epidemiol Date: 2008-12-03 Impact factor: 7.196