Literature DB >> 3463202

Prednisone stimulation of erythropoiesis in leukemic children during remission.

M D Amylon, S P Perrine, B E Glader.   

Abstract

Children with acute leukemia in remission manifest reticulocytosis and a significant increase in hemoglobin concentration (mean increment of 2.3 +/- 1.1 g/dl) following prednisone pulse therapy. This hemoglobin increment is not associated with changes in serum erythropoietin activity. It is speculated that this stimulation of red cell production may be a direct effect of steroids on erythroid progenitor cells.

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Year:  1986        PMID: 3463202     DOI: 10.1002/ajh.2830230213

Source DB:  PubMed          Journal:  Am J Hematol        ISSN: 0361-8609            Impact factor:   10.047


  1 in total

1.  The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors.

Authors:  O Wessely; E M Deiner; H Beug; M von Lindern
Journal:  EMBO J       Date:  1997-01-15       Impact factor: 11.598

  1 in total

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