Literature DB >> 34625363

Modulation of membrane-cytoskeleton interactions: ezrin as key player.

Lei-Miao Yin1, Michael Schnoor2.   

Abstract

Membrane-cytoskeleton interactions (MCIs) are mediated by actin-binding proteins (ABPs). Ezrin is a crucial ABP that links membranes to actin filaments during lamellipodia formation, cell polarization, and migration. We discuss the concept of MCI and the potential of ezrin as a druggable target for treating inflammatory diseases and cancers.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  actin binding-proteins; asthma; cancer; ezrin; membrane–cytoskeleton interactions

Mesh：

Substances：

Year:  2021        PMID： 34625363     DOI： 10.1016/j.tcb.2021.09.005

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  3 in total

1.  DPYSL2 interacts with JAK1 to mediate breast cancer cell migration.

Authors:  Areej Abu Rmaileh; Balakrishnan Solaimuthu; Anees Khatib; Shirel Lavi; Mayur Tanna; Arata Hayashi; Michal Ben Yosef; Michal Lichtenstein; Nir Pillar; Yoav D Shaul
Journal:  J Cell Biol       Date:  2022-05-16       Impact factor: 8.077

2.  The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness.

Authors:  Hong-Kai Yuan; Jin Lu; Xue-Ling Wang; Zhi-Ying Lv; Bo Li; Weiliang Zhu; Yong-Qing Yang; Lei-Miao Yin
Journal:  Front Pharmacol       Date:  2022-06-16       Impact factor: 5.988

3.  Editorial: Evolution, Emerging Functions and Structure of Actin-Binding Proteins.

Authors:  Lei-Miao Yin; Michael Schnoor; Chang-Duk Jun
Journal:  Front Cell Dev Biol       Date:  2021-12-10
  3 in total

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