| Literature DB >> 3462380 |
R I Vogel, I B Lamster, S A Wechsler, B Macedo, L J Hartley, J A Macedo.
Abstract
A double-blind study was undertaken to determine the effects of megadose ascorbic acid supplementation on plasma ascorbate levels, polymorphonuclear neutrophil (PMN) chemotaxis and clinical and biochemical determinations of inflammatory progression in individuals with a mean daily ascorbate intake level of approximately twice the recommended daily allowances. Results indicate that although the group receiving ascorbate supplementation demonstrated a significant increase in plasma levels of the vitamin as compared to a placebo group, no significant differences with respect to PMN chemotaxis or responses to experimental gingivitis were found between the groups.Entities:
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Year: 1986 PMID: 3462380 DOI: 10.1902/jop.1986.57.8.472
Source DB: PubMed Journal: J Periodontol ISSN: 0022-3492 Impact factor: 6.993