| Literature DB >> 34622255 |
Zhouyang Huang1, A Paden King1, James Lovett2, Barry Lai3, Joshua J Woods1,4, Hugh H Harris2, Justin J Wilson1.
Abstract
The photophysical and photochemical properties of two Pt(IV)Re(I) conjugates were studied via both experimental and computational methods. Both conjugates exhibit modest photocytotoxicity against ovarian cancer cells. X-ray fluorescence microscopy showed that Pt and Re colocalize in cells whether they had been irradiated or not. This work demonstrates the potential of photoactivated multilimetallic agents for combating cancer.Entities:
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Year: 2021 PMID： 34622255 DOI： 10.1039/d1cc04669a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222