Literature DB >> 34617178

Cytoprotective and Antioxidant Effects of Meconic Acid in Model Systems.

S V Kozin1,2, A A Kravtsov3,4, S V Kravchenko3, L I Ivashchenko3.   

Abstract

We studied the antioxidant and cytoprotective effects of meconic acid in the model systems. Meconic acid, similar to commercial drug Mexidol, reduced the intensity of chemiluminescence in the model system of yolk lipoproteins. Meconic acid also reduced the toxic effect of glutamate on neurons in the primary cerebellar culture, but had no effect on cell viability under normal conditions.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  cerebellar neuron culture; chemiluminescence; glutamate toxicity; meconic acid

Mesh：

Substances：

Year:  2021        PMID： 34617178     DOI： 10.1007/s10517-021-05281-6

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  6 in total

1.  Neuroprotector effect of comenic acid against cytotoxic action of glutamate in vitro in cultured neurons of lead-poisoned rat pups.

Authors:  A A Kravtsov; A Ya Shurygin; N S Skorokhod; L G Khaspekov
Journal:  Bull Exp Biol Med       Date:  2011-02       Impact factor: 0.804

Review 2.  Neuronal Cell Death.

Authors:  Michael Fricker; Aviva M Tolkovsky; Vilmante Borutaite; Michael Coleman; Guy C Brown
Journal:  Physiol Rev       Date:  2018-04-01       Impact factor: 37.312

3.  The therapeutic effect of chelidonic acid on ulcerative colitis.

Authors:  Dae-Seung Kim; Su-Jin Kim; Min-Cheol Kim; Yong-Deok Jeon; Jae-young Um; Seung-Heon Hong
Journal:  Biol Pharm Bull       Date:  2012       Impact factor: 2.233

4.  Neurotrophic Action of Comenic Acid and Its Derivatives Potassium Comenate and Calcium Comenate.

Authors:  L V Shurygina; E I Zlishcheva; A A Kravtsov
Journal:  Bull Exp Biol Med       Date:  2018-08-18       Impact factor: 0.804

5.  Antioxidant and Antiamnestic Effects of Potassium Comenate and Comenic Acid under Conditions of Normobaric Hypoxia with Hypercapnia.

Authors:  L V Shurygina; E I Zlishcheva; A N Kravtsova; A A Kravtsov
Journal:  Bull Exp Biol Med       Date:  2017-07-26       Impact factor: 0.804

6.  Comenic acid prevents post-stress enhancement of long-term potentiation in rat hippocampus.

Authors:  R V Kondratenko; A N Chepkova; A Ya Shurygin; V G Skrebitskii
Journal:  Bull Exp Biol Med       Date:  2003-11       Impact factor: 0.804
  6 in total

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