| Literature DB >> 3461485 |
T K Hughes, E M Smith, J E Blalock.
Abstract
Ia antigens were previously shown to be B-cell receptors for transformed cell surface glycoproteins (TCSG). Ia antigen recognition of TCSG subsequently initiated interferon production. These findings have been exploited to highly purify TCSG from mouse L (H-2k) cells in one step by Iak antigen Sepharose affinity chromatography. These results point to the highly specific recognition of TCSG by Ia antigens and the B-cells on which they reside. The implications and applications of these studies are discussed.Entities:
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Year: 1986 PMID： 3461485 DOI： 10.3181/00379727-182-4-rc2
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN： 0037-9727