Literature DB >> 34609905

COVID-19 Vaccines: Adenoviral Vectors.

Catherine Jacob-Dolan1,2,3, Dan H Barouch1,2,3.   

Abstract

The worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the unprecedented pace of development of multiple vaccines. This review evaluates how adenovirus (Ad) vector platforms have been leveraged in response to this pandemic. Ad vectors have been used in the past for vaccines against other viruses, most notably HIV and Ebola, but they never have been produced, distributed, or administered to humans at such a large scale. Several different serotypes of Ads encoding SARS-CoV-2 Spike have been tested and found to be efficacious against COVID-19. As vaccine rollouts continue and the number of people receiving these vaccines increases, we will continue to learn about this vaccine platform for COVID-19 prevention and control.

Entities:  

Keywords:  COVID-19; SARS-CoV-2; adenovirus; vaccine; vector

Mesh：

Substances：

Year:  2021        PMID： 34609905      PMCID： PMC8795482          DOI： 10.1146/annurev-med-012621-102252

Source DB:  PubMed          Journal:  Annu Rev Med        ISSN： 0066-4219            Impact factor:   13.739


  84 in total

1.  Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial.

Authors:  Nawal Al Kaabi; Yuntao Zhang; Shengli Xia; Yunkai Yang; Manaf M Al Qahtani; Najiba Abdulrazzaq; Majed Al Nusair; Mohamed Hassany; Jaleela S Jawad; Jehad Abdalla; Salah Eldin Hussein; Shamma K Al Mazrouei; Maysoon Al Karam; Xinguo Li; Xuqin Yang; Wei Wang; Bonan Lai; Wei Chen; Shihe Huang; Qian Wang; Tian Yang; Yang Liu; Rui Ma; Zaidoon M Hussain; Tehmina Khan; Mohammed Saifuddin Fasihuddin; Wangyang You; Zhiqiang Xie; Yuxiu Zhao; Zhiwei Jiang; Guoqing Zhao; Yanbo Zhang; Sally Mahmoud; Islam ElTantawy; Peng Xiao; Ashish Koshy; Walid Abbas Zaher; Hui Wang; Kai Duan; An Pan; Xiaoming Yang
Journal:  JAMA       Date:  2021-07-06       Impact factor: 56.272

2.  The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex.

Authors:  Berend Jan Bosch; Ruurd van der Zee; Cornelis A M de Haan; Peter J M Rottier
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

Review 3.  From vaccines to memory and back.

Authors:  Federica Sallusto; Antonio Lanzavecchia; Koichi Araki; Rafi Ahmed
Journal:  Immunity       Date:  2010-10-29       Impact factor: 31.745

4.  ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets.

Authors:  Glenn A Marsh; Alexander J McAuley; Gough G Au; Sarah Riddell; Daniel Layton; Nagendrakumar B Singanallur; Rachel Layton; Jean Payne; Peter A Durr; Hannah Bender; Jennifer A Barr; John Bingham; Victoria Boyd; Sheree Brown; Matthew P Bruce; Kathie Burkett; Teresa Eastwood; Sarah Edwards; Tamara Gough; Kim Halpin; Jenni Harper; Clare Holmes; William S J Horman; Petrus Jansen van Vuren; Suzanne Lowther; Kate Maynard; Kristen D McAuley; Matthew J Neave; Timothy Poole; Christina Rootes; Brenton Rowe; Elisha Soldani; Vittoria Stevens; Cameron R Stewart; Willy W Suen; Mary Tachedjian; Shawn Todd; Lee Trinidad; Duane Walter; Naomi Watson; Trevor W Drew; Sarah C Gilbert; Teresa Lambe; S S Vasan
Journal:  NPJ Vaccines       Date:  2021-05-10       Impact factor: 7.344

5.  Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans.

Authors:  Galit Alter; Jingyou Yu; Jinyan Liu; Abishek Chandrashekar; Erica N Borducchi; Lisa H Tostanoski; Katherine McMahan; Catherine Jacob-Dolan; David R Martinez; Aiquan Chang; Tochi Anioke; Michelle Lifton; Joseph Nkolola; Kathryn E Stephenson; Caroline Atyeo; Sally Shin; Paul Fields; Ian Kaplan; Harlan Robins; Fatima Amanat; Florian Krammer; Ralph S Baric; Mathieu Le Gars; Jerald Sadoff; Anne Marit de Groot; Dirk Heerwegh; Frank Struyf; Macaya Douoguih; Johan van Hoof; Hanneke Schuitemaker; Dan H Barouch
Journal:  Nature       Date:  2021-06-09       Impact factor: 49.962

6.  A new coronavirus associated with human respiratory disease in China.

Authors:  Fan Wu; Su Zhao; Bin Yu; Yan-Mei Chen; Wen Wang; Zhi-Gang Song; Yi Hu; Zhao-Wu Tao; Jun-Hua Tian; Yuan-Yuan Pei; Ming-Li Yuan; Yu-Ling Zhang; Fa-Hui Dai; Yi Liu; Qi-Min Wang; Jiao-Jiao Zheng; Lin Xu; Edward C Holmes; Yong-Zhen Zhang
Journal:  Nature       Date:  2020-02-03       Impact factor: 49.962

7.  Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters.

Authors:  Lisa H Tostanoski; Frank Wegmann; Amanda J Martinot; Carolin Loos; Katherine McMahan; Noe B Mercado; Jingyou Yu; Chi N Chan; Stephen Bondoc; Carly E Starke; Michael Nekorchuk; Kathleen Busman-Sahay; Cesar Piedra-Mora; Linda M Wrijil; Sarah Ducat; Jerome Custers; Caroline Atyeo; Stephanie Fischinger; John S Burke; Jared Feldman; Blake M Hauser; Timothy M Caradonna; Esther A Bondzie; Gabriel Dagotto; Makda S Gebre; Catherine Jacob-Dolan; Zijin Lin; Shant H Mahrokhian; Felix Nampanya; Ramya Nityanandam; Laurent Pessaint; Maciel Porto; Vaneesha Ali; Dalia Benetiene; Komlan Tevi; Hanne Andersen; Mark G Lewis; Aaron G Schmidt; Douglas A Lauffenburger; Galit Alter; Jacob D Estes; Hanneke Schuitemaker; Roland Zahn; Dan H Barouch
Journal:  Nat Med       Date:  2020-09-03       Impact factor: 53.440

8.  Thrombotic Thrombocytopenia after Ad26.COV2.S Vaccination - Response from the Manufacturer.

Authors:  Jerald Sadoff; Kourtney Davis; Macaya Douoguih
Journal:  N Engl J Med       Date:  2021-04-16       Impact factor: 91.245

9.  Convergent antibody responses to SARS-CoV-2 in convalescent individuals.

Authors:  Davide F Robbiani; Christian Gaebler; Frauke Muecksch; Julio C C Lorenzi; Zijun Wang; Alice Cho; Marianna Agudelo; Christopher O Barnes; Anna Gazumyan; Shlomo Finkin; Thomas Hägglöf; Thiago Y Oliveira; Charlotte Viant; Arlene Hurley; Hans-Heinrich Hoffmann; Katrina G Millard; Rhonda G Kost; Melissa Cipolla; Kristie Gordon; Filippo Bianchini; Spencer T Chen; Victor Ramos; Roshni Patel; Juan Dizon; Irina Shimeliovich; Pilar Mendoza; Harald Hartweger; Lilian Nogueira; Maggi Pack; Jill Horowitz; Fabian Schmidt; Yiska Weisblum; Eleftherios Michailidis; Alison W Ashbrook; Eric Waltari; John E Pak; Kathryn E Huey-Tubman; Nicholas Koranda; Pauline R Hoffman; Anthony P West; Charles M Rice; Theodora Hatziioannou; Pamela J Bjorkman; Paul D Bieniasz; Marina Caskey; Michel C Nussenzweig
Journal:  Nature       Date:  2020-06-18       Impact factor: 69.504

10.  Broad neutralization of SARS-related viruses by human monoclonal antibodies.

Authors:  Anna Z Wec; Daniel Wrapp; Andrew S Herbert; Daniel P Maurer; Denise Haslwanter; Mrunal Sakharkar; Rohit K Jangra; M Eugenia Dieterle; Asparouh Lilov; Deli Huang; Longping V Tse; Nicole V Johnson; Ching-Lin Hsieh; Nianshuang Wang; Juergen H Nett; Elizabeth Champney; Irina Burnina; Michael Brown; Shu Lin; Melanie Sinclair; Carl Johnson; Sarat Pudi; Robert Bortz; Ariel S Wirchnianski; Ethan Laudermilch; Catalina Florez; J Maximilian Fels; Cecilia M O'Brien; Barney S Graham; David Nemazee; Dennis R Burton; Ralph S Baric; James E Voss; Kartik Chandran; John M Dye; Jason S McLellan; Laura M Walker
Journal:  Science       Date:  2020-06-15       Impact factor: 47.728
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  9 in total

Review 1.  [Overview of COVID-19 vaccines licensed in the EU-from technology via clinical trial to registration].

Authors:  Eberhard Hildt
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2022-10-18       Impact factor: 1.595

2.  m6A Regulator-Mediated Methylation Modification Patterns and Characteristics in COVID-19 Patients.

Authors:  Xin Qing; Qian Chen; Ke Wang
Journal:  Front Public Health       Date:  2022-05-17

Review 3.  Viral Vectors for the in Vivo Delivery of CRISPR Components: Advances and Challenges.

Authors:  Misganaw Asmamaw Mengstie
Journal:  Front Bioeng Biotechnol       Date:  2022-05-12

4.  COVID-19 pandemic is associated with increased sleep disturbances and mental health symptoms but not help-seeking: a cross-sectional nation-wide study.

Authors:  Claudia Roberta de Castro Moreno; Silvia G Conway; Márcia Assis; Pedro Rodrigues Genta; Daniela V Pachito; Almir Tavares; Danilo A Sguillar; Gustavo Moreira; Luciano F Drager; Andrea Bacelar
Journal:  Sleep Sci       Date:  2022 Jan-Mar

5.  Criteria for judging the immune markers of COVID-19 disease vaccines.

Authors:  Nan Lin; Haoxuan Fu; Dan Pu; Yuxin Quan; Yueyi Li; Xiaomeng Yin; Yuhao Wei; Hang Wang; Xuelei Ma; Xiawei Wei
Journal:  MedComm (2020)       Date:  2021-12-31

Review 6.  Pathological and protective roles of dendritic cells in Mycobacterium tuberculosis infection: Interaction between host immune responses and pathogen evasion.

Authors:  Hongmin Kim; Sung Jae Shin
Journal:  Front Cell Infect Microbiol       Date:  2022-07-28       Impact factor: 6.073

7.  Comparison of IgA, IgG, and Neutralizing Antibody Responses Following Immunization With Moderna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson, and Sinopharm's COVID-19 Vaccines.

Authors:  Tomabu Adjobimey; Julia Meyer; Leander Sollberg; Michael Bawolt; Christina Berens; Peđa Kovačević; Anika Trudić; Marijo Parcina; Achim Hoerauf
Journal:  Front Immunol       Date:  2022-06-21       Impact factor: 8.786

8.  Safety and immune response kinetics of GRAd-COV2 vaccine: phase 1 clinical trial results.

Authors:  Chiara Agrati; Concetta Castilletti; Simone Battella; Eleonora Cimini; Giulia Matusali; Andrea Sommella; Alessandra Sacchi; Francesca Colavita; Alessandra M Contino; Veronica Bordoni; Silvia Meschi; Giulia Gramigna; Federica Barra; Germana Grassi; Licia Bordi; Daniele Lapa; Stefania Notari; Rita Casetti; Aurora Bettini; Massimo Francalancia; Federica Ciufoli; Alessandra Vergori; Serena Vita; Michela Gentile; Angelo Raggioli; Maria M Plazzi; Antonella Bacchieri; Emanuele Nicastri; Andrea Antinori; Stefano Milleri; Simone Lanini; Stefano Colloca; Enrico Girardi; Roberto Camerini; Giuseppe Ippolito; Francesco Vaia; Antonella Folgori; Stefania Capone
Journal:  NPJ Vaccines       Date:  2022-09-24       Impact factor: 9.399

Review 9.  Recombinant vaccines in 2022: a perspective from the cell factory.

Authors:  Marianna Teixeira de Pinho Favaro; Jan Atienza-Garriga; Carlos Martínez-Torró; Eloi Parladé; Esther Vázquez; José Luis Corchero; Neus Ferrer-Miralles; Antonio Villaverde
Journal:  Microb Cell Fact       Date:  2022-10-05       Impact factor: 6.352
  9 in total

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