Literature DB >> 3460927

[Cloned fragment of human alphoid DNA--a molecular marker of the pericentromeric region of chromosome 18].

I A Aleksandrov, Iu B Iurov, S P Mitkevich, V M Gindilis.   

Abstract

From the library of cloned fragments of human DNA we have isolated two recombinant plasmids containing alphoid DNA sequences pBRHS13, pBRHS65. Both cloned sequences hybridized in situ predominantly to pericentromeric regions of chromosome 18 and with less intensity to pericentromeric regions of chromosomes 2, 9, 20, and were characterized by populational copy number polymorphism in homologous chromosomes. These sequences may appear very useful in the diagnostics and cytogenetic analysis of chromosomal aberrations and in studies of polymorphisms of heterochromatic regions of human chromosomes.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3460927

Source DB:  PubMed          Journal:  Genetika        ISSN： 0016-6758


  3 in total

1.  The phylogeny of human chromosome specific alpha satellites.

Authors:  I A Alexandrov; S P Mitkevich; Y B Yurov
Journal:  Chromosoma       Date:  1988       Impact factor: 4.316

2.  High resolution multicolor fluorescence in situ hybridization using cyanine and fluorescein dyes: rapid chromosome identification by directly fluorescently labeled alphoid DNA probes.

Authors:  Y B Yurov; I V Soloviev; S G Vorsanova; B Marcais; G Roizes; R Lewis
Journal:  Hum Genet       Date:  1996-03       Impact factor: 4.132

3.  Application of cloned satellite DNA sequences to molecular-cytogenetic analysis of constitutive heterochromatin heteromorphisms in man.

Authors:  Y B Yurov; S P Mitkevich; I A Alexandrov
Journal:  Hum Genet       Date:  1987-06       Impact factor: 4.132
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.