Literature DB >> 34607324

Performance evaluation of dual-ended readout PET detectors based on BGO arrays with different reflector arrangements.

Junwei Du1, Qian Wang1, Chih-Chieh Liu1, Jinyi Qi1, Simon R Cherry1.   

Abstract

OBJECTIVE: Dual-ended readout depth-encoding detectors based on bismuth germanate (BGO) scintillation crystal arrays are good candidates for high-sensitivity small animal positron emission tomography used for very-low-dose imaging. In this paper, the performance of three dual-ended readout detectors based on 15 × 15 BGO arrays with three different reflector arrangements and 8 × 8 silicon photomultiplier arrays were evaluated and compared. APPROACH: The three BGO arrays, denoted wo-ILG (without internal light guide), wp-ILG (with partial internal light guide), and wf-ILG (with full internal light guide), share a pitch size of 1.6 mm and thickness of 20 mm. Toray E60 with a thickness of 50μm was used as inter-crystal reflector. All reflector lengths in the wo-ILG and wf-ILG BGO arrays were 20 and 18 mm, respectively; the reflectors in the wp-ILG BGO array were 18 mm at the central region of the array and 20 mm at the edge. By using 18 mm reflectors, part of the crystals in the wp-ILG and wf-ILG BGO arrays worked as internal light guides. MAIN
RESULTS: The results showed that the detector based on the wo-ILG BGO array provided the best flood histogram. The energy, timing and DOI resolutions of the three detectors were similar. The energy resolutions full width at half maximum (FWHM value) based on the wo-ILG, wp-ILG and wf-ILG BGO arrays were 27.2 ± 3.9%, 28.7 ± 4.6%, and 29.5 ± 4.7%, respectively. The timing resolutions (FWHM value) were 4.7 ± 0.5 ns, 4.9 ± 0.5 ns, and 5.0 ± 0.6 ns, respectively. The DOI resolution (FWHM value) were 3.0 ± 0.2 mm, 2.9 ± 0.2 mm, and 3.0 ± 0.2 mm, respectively. Over all, the wo-ILG detector provided the best performance.
© 2021 Institute of Physics and Engineering in Medicine.

Entities:  

Keywords:  BGO; DOI; PET; dual-ended

Mesh:

Substances:

Year:  2021        PMID: 34607324      PMCID: PMC8571945          DOI: 10.1088/1361-6560/ac2c9c

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   4.174


  29 in total

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Authors:  Guus A M S van Dongen; Ronald Boellaard; Danielle J Vugts
Journal:  Nat Biomed Eng       Date:  2020-08       Impact factor: 25.671

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Authors:  Yiping Shao; Xishan Sun; Kejian A Lan; Chad Bircher; Kai Lou; Zhi Deng
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8.  NEMA NU-4 performance evaluation of PETbox4, a high sensitivity dedicated PET preclinical tomograph.

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Journal:  Phys Med Biol       Date:  2013-05-10       Impact factor: 3.609

9.  Evaluation of a BGO-Based PET System for Single-Cell Tracking Performance by Simulation and Phantom Studies.

Authors:  Yu Ouyang; Tae Jin Kim; Guillem Pratx
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Authors:  Kyung Oh Jung; Tae Jin Kim; Jung Ho Yu; Siyeon Rhee; Wei Zhao; Byunghang Ha; Kristy Red-Horse; Sanjiv Sam Gambhir; Guillem Pratx
Journal:  Nat Biomed Eng       Date:  2020-06-15       Impact factor: 25.671

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  1 in total

Review 1.  Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.

Authors:  Haewook Park; Minseok Yi; Jae Sung Lee
Journal:  Biomed Eng Lett       Date:  2022-07-16
  1 in total

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