Literature DB >> 34604335

Onycholemmal Horn: An Exceedingly Rare Subungual Tumor.

Valeria Olvera-Rodríguez1, Sonia Toussaint-Caire2, Judith Domínguez-Cherit3.   

Abstract

The onycholemmal horn is an exceedingly rare subungual tumor characterized by trichilemmal-like keratinization pattern. The only previous instance of onycholemmal horn dates back to 1983 when Haneke reported a keratotic subungual tumor clinically and histologically comparable to a trichilemmal horn. No other case of this condition has been reported so far. We present the case of a 72-year-old female patient, with a history of a slowly growing tumor originating from the nail bed epithelium of the left thumb. The lesion was surgically removed, and pathological examination was consistent with the diagnosis of an onycholemmal horn. Additionally, this study aims to elucidate the correlation between the onycholemmal and trichilemmal keratinization.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Nail; Nail disorder; Nail tumor; Onycholemmal horn; Onycholemmal keratinization; Onychopathology; Trichilemmal horn

Year:  2021        PMID: 34604335      PMCID: PMC8436694          DOI: 10.1159/000516303

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  13 in total

Review 1.  Tumors of the nail unit.

Authors:  S J Salasche; I F Orengo
Journal:  J Dermatol Surg Oncol       Date:  1992-08

2.  Expression of follicular sheath keratins in the normal nail with special reference to the morphological analysis of the distal nail unit.

Authors:  Christophe Perrin
Journal:  Am J Dermatopathol       Date:  2007-12       Impact factor: 1.533

3.  The 2 clinical subbands of the distal nail unit and the nail isthmus. Anatomical explanation and new physiological observations in relation to the nail growth.

Authors:  Christophe Perrin
Journal:  Am J Dermatopathol       Date:  2008-06       Impact factor: 1.533

4.  Wichtige maligne und neue Nageltumoren.

Authors:  Eckart Haneke
Journal:  J Dtsch Dermatol Ges       Date:  2017-04       Impact factor: 5.584

5.  Onycholemmal variant of keratoacanthoma centrifugum marginatum as an expression of mutated committed stem cells in a conceptual pathway.

Authors:  Steven Kossard; Alvand Amiri
Journal:  Australas J Dermatol       Date:  2020-03-12       Impact factor: 2.875

Review 6.  Tumors of the nail unit. A review. Part II: acquired localized longitudinal pachyonychia and masked nail tumors.

Authors:  Christophe Perrin
Journal:  Am J Dermatopathol       Date:  2013-10       Impact factor: 1.533

7.  'Onycholemmal' horn.

Authors:  E Haneke
Journal:  Dermatologica       Date:  1983

8.  Trichilemmal keratosis (horn): a light and electron microscopic study.

Authors:  S Kimura
Journal:  J Cutan Pathol       Date:  1983-02       Impact factor: 1.587

9.  Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed.

Authors:  C Perrin; L Langbein; J Schweizer
Journal:  Br J Dermatol       Date:  2004-08       Impact factor: 9.302

Review 10.  Trichilemmal horn: case presentation and literature review.

Authors:  D J DiMaio; P R Cohen
Journal:  J Am Acad Dermatol       Date:  1998-08       Impact factor: 11.527

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