Literature DB >> 34604333

Perianal Hyperhidrosis Successfully Treated with Botulinum Toxin A.

Leandra Reguero Del Cura1, Marta Drake Monfort1, Adrian De Quintana Sancho1, Marcos Antonio González López1.   

Abstract

Perianal hyperhidrosis (HH) is a rare form of primary focal HH and may become a major problem for the patient with a significant psychosocial burden and negative impact on the quality of life. Botulinum toxin injections are widely used as a second-line treatment option for axillary, palmar, and plantar HH with a good safety profile. Herein, we pre-sent a case of primary perianal HH successfully treated with Botulinum toxin A at a dose higher than that previously reported in literature, with a longer response, a higher degree of satisfaction, and no adverse effects. Moreover, we review the main aspects of the perianal anatomy that are essential to carry out the technique correctly and make dermatologists achieve expertise with the procedure.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Botulinum toxin A; Dermatology; Hyperhidrosis; Intradermal; Therapy

Year:  2021        PMID: 34604333      PMCID: PMC8436621          DOI: 10.1159/000515492

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  8 in total

Review 1.  Pharmacology of botulinum toxin.

Authors:  W Huang; J A Foster; A S Rogachefsky
Journal:  J Am Acad Dermatol       Date:  2000-08       Impact factor: 11.527

2.  Skin appendage involvement in anal intraepithelial neoplasia.

Authors:  P P Skinner; O A Ogunbiyi; J H Scholefield; R D Start; J H Smith; F Sharp; K Rogers
Journal:  Br J Surg       Date:  1997-05       Impact factor: 6.939

3.  Results of a 10-year follow-up study of botulinum toxin A therapy for primary axillary hyperhidrosis in Australia.

Authors:  Robert Rosen; Thomas Stewart
Journal:  Intern Med J       Date:  2018-03       Impact factor: 2.048

Review 4.  Botulinum toxin: Pharmacology and injectable administration for the treatment of primary hyperhidrosis.

Authors:  Shiri Nawrocki; Jisun Cha
Journal:  J Am Acad Dermatol       Date:  2019-12-04       Impact factor: 11.527

5.  Botulinum toxin type A in the treatment of primary axillary hyperhidrosis: a 52-week multicenter double-blind, randomized, placebo-controlled study of efficacy and safety.

Authors:  Nicholas J Lowe; Dee Anna Glaser; Nina Eadie; Simon Daggett; Jonathan W Kowalski; Pan-Yu Lai
Journal:  J Am Acad Dermatol       Date:  2007-02-15       Impact factor: 11.527

6.  Clinical differentiation of primary from secondary hyperhidrosis.

Authors:  Hobart W Walling
Journal:  J Am Acad Dermatol       Date:  2011-02-18       Impact factor: 11.527

7.  Focal hyperhidrosis of the anal fold: successful treatment with botulinum toxin A.

Authors:  Falk G Bechara; Michael Sand; Reinhard K Achenbach; Daniel Sand; Peter Altmeyer; Klaus Hoffmann
Journal:  Dermatol Surg       Date:  2007-08       Impact factor: 3.398

Review 8.  Botulinum Toxin Injection for Treatment of Chronic Anal Fissure: Is There Any Dose-Dependent Efficiency? A Meta-Analysis.

Authors:  Adam Bobkiewicz; Wojciech Francuzik; Lukasz Krokowicz; Adam Studniarek; Witold Ledwosiński; Jacek Paszkowski; Michal Drews; Tomasz Banasiewicz
Journal:  World J Surg       Date:  2016-12       Impact factor: 3.352

  8 in total

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