Literature DB >> 34604325

Fungal Viability of Nail Dust from Onychomycosis Abrasion: A Pilot Study.

Nilton Di Chiacchio1, Gustavo de Sá Menezes Carvalho2, Nilton Gioia Di Chiacchio1, Cristina Diniz Borges Figueira de Mello1, John Verrinder Veasey2.   

Abstract

INTRODUCTION: Onychomycosis is a frequent complaint in dermatological practice and corresponds to the most common nail disease. The treatment of onychomycosis remains a challenge, as several factors end up compromising and making treatment difficult. Nail abrasion is considered a useful method in many cases. However, there is controversy about this approach, as there is an aerosol formation that could contaminate the environment and cause fungal changes or hypersensitivity reactions by the disseminated dust. We conducted a pilot study to investigate the fungal viability of nail particles from nails with onychomycosis after abrasion procedure.
METHODS: In this study, nail dust from the gloves and mask, used in the procedure, was collected from 9 patients with clinical and dermoscopic diagnoses of onychomycosis.
RESULTS: Hyaline septate hyphae were found in 12 materials (gloves and/or masks) from 7 patients. However, these hyphae were morphologically deformed or mutilated in all exams. In Mycosel® agar, there was no growth of any fungus. DISCUSSION/
CONCLUSION: The absence of dermatophyte isolation in all fungal cultures may demonstrate that the deformed fungal structures shown are not viable and would not present risks of contamination after nail abrasion.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Clinical dermatology; Dermatomycosis; Direct mycological examination; Mycotic examination; Nail abrasion; Nail fungus; Onychomycosis

Year:  2021        PMID: 34604325      PMCID: PMC8436625          DOI: 10.1159/000516307

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  5 in total

1.  Treatment options--development of consensus guidelines.

Authors:  M Lecha; I Effendy; M Feuilhade de Chauvin; N Di Chiacchio; R Baran
Journal:  J Eur Acad Dermatol Venereol       Date:  2005-09       Impact factor: 6.166

2.  Painless technique for debridement of onychodystrophic nails.

Authors:  Krysta Lin; Shari R Lipner
Journal:  J Am Acad Dermatol       Date:  2019-05-29       Impact factor: 11.527

3.  Nail debridement after ablative fractional laser treatment and occlusive dressing with urea 20% cream: An alternative to nail extraction.

Authors:  Yu Seok Jung; Ji Hae Lee; Gyong Moon Kim; Jung Min Bae
Journal:  J Am Acad Dermatol       Date:  2017-09       Impact factor: 11.527

4.  Nail abrasion: a new treatment for ingrown toe-nails.

Authors:  N Maeda; N Mizuno; K Ichikawa
Journal:  J Dermatol       Date:  1990-12       Impact factor: 4.005

5.  Nail dust aerosols from onychomycotic toenails. Part II. Clinical and serologic aspects. 1984.

Authors:  C Abramson; J Wilton
Journal:  J Am Podiatr Med Assoc       Date:  1992-02
  5 in total

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