Jian Wang1, Peiwei Yi2,3, Yaobin Huang1, Qinqin Yu4, Yingjie Mei5, Jialing Chen1, Yanqiu Feng2,3, Xiaodong Zhang1. 1. Department of Medical Imaging, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics Guangdong Province), Guangzhou, China. 2. School of Biomedical Engineering, Southern Medical University, Guangzhou, China. 3. Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China. 4. Department of Medical Imaging, Shanghai General Hospital, Shanghai, China. 5. China International Center, Philips Healthcare, Guangzhou, China.
Abstract
BACKGROUND: Marrow fat exists as a distinct adipose tissue and plays a critical role in affecting both the quantity and quality of bone. However, the effect of soccer training on marrow fat has been rarely reported. This study aims to evaluate and characterize the marrow fat content and composition in different bone areas of soccer players and age-matched healthy subjects using proton magnetic resonance spectroscopy (1H-MRS). METHODS: Between May 2020 and June 2020, 20 professional soccer players (20.7±0.9 years) and 20 age-matched healthy subjects (21.2±0.8 years) were enrolled in this cross-sectional study. The 1H-MRS were acquired from the 3rd lumbar vertebrae, bilateral femoral necks, and distal tibias of all subjects using a single-voxel point-resolved spatially localized spectroscopy (PRESS) sequence. Four soccer players underwent a second magnetic resonance (MR) examination within a 30-minute interval after the initial scan to evaluate test-retest reproducibility. Inter- and intra-observer measurement reliabilities were assessed using 10 randomly selected spectra from the soccer players group. All spectra were processed using the jMRUI software package (http://www.jmrui.eu/). Quantified water and lipid signals were used to calculate fat content (FC) and the unsaturated fatty index (UI). RESULTS: Compared with healthy subjects, we found that soccer players had a lower FC in L3 and bilateral femoral necks and higher UI in the left femoral neck (P<0.05). All FC and UI values of the bilateral distal tibias showed no significant differences between the two groups (P>0.05). The UI values of the right femoral neck or distal tibia were markedly higher than the left side in both inactive subjects and soccer players (P<0.05, except for the femoral neck in players), and there were notable ΔUI differences in the lower limbs between the soccer players and the healthy subjects (P<0.05). CONCLUSIONS: Soccer practice can be considered a positive sport that contributes to decreasing FC in lumbar vertebrae and femoral necks and increasing the UI in femoral necks. Quantitative MRS provides an ideal modality to predict marrow fat metabolism caused by mechanical stimulation. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
BACKGROUND: Marrow fat exists as a distinct adipose tissue and plays a critical role in affecting both the quantity and quality of bone. However, the effect of soccer training on marrow fat has been rarely reported. This study aims to evaluate and characterize the marrow fat content and composition in different bone areas of soccer players and age-matched healthy subjects using proton magnetic resonance spectroscopy (1H-MRS). METHODS: Between May 2020 and June 2020, 20 professional soccer players (20.7±0.9 years) and 20 age-matched healthy subjects (21.2±0.8 years) were enrolled in this cross-sectional study. The 1H-MRS were acquired from the 3rd lumbar vertebrae, bilateral femoral necks, and distal tibias of all subjects using a single-voxel point-resolved spatially localized spectroscopy (PRESS) sequence. Four soccer players underwent a second magnetic resonance (MR) examination within a 30-minute interval after the initial scan to evaluate test-retest reproducibility. Inter- and intra-observer measurement reliabilities were assessed using 10 randomly selected spectra from the soccer players group. All spectra were processed using the jMRUI software package (http://www.jmrui.eu/). Quantified water and lipid signals were used to calculate fat content (FC) and the unsaturated fatty index (UI). RESULTS: Compared with healthy subjects, we found that soccer players had a lower FC in L3 and bilateral femoral necks and higher UI in the left femoral neck (P<0.05). All FC and UI values of the bilateral distal tibias showed no significant differences between the two groups (P>0.05). The UI values of the right femoral neck or distal tibia were markedly higher than the left side in both inactive subjects and soccer players (P<0.05, except for the femoral neck in players), and there were notable ΔUI differences in the lower limbs between the soccer players and the healthy subjects (P<0.05). CONCLUSIONS: Soccer practice can be considered a positive sport that contributes to decreasing FC in lumbar vertebrae and femoral necks and increasing the UI in femoral necks. Quantitative MRS provides an ideal modality to predict marrow fat metabolism caused by mechanical stimulation. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
Entities:
Keywords:
Magnetic resonance spectroscopy (MRS); bone marrow; fat content (FC); soccer players; unsaturated fatty index (UI)
Authors: Mark C Horowitz; Ryan Berry; Brandon Holtrup; Zachary Sebo; Tracy Nelson; Jackie A Fretz; Dieter Lindskog; Jennifer L Kaplan; Gene Ables; Matthew S Rodeheffer; Clifford J Rosen Journal: Adipocyte Date: 2017-08-24 Impact factor: 4.534
Authors: Daniel L Belavy; Matthew J Quittner; Nicola D Ridgers; Adnan Shiekh; Timo Rantalainen; Guy Trudel Journal: J Bone Miner Res Date: 2018-01-16 Impact factor: 6.741
Authors: Robert C Bertheau; Roberto Lorbeer; Johanna Nattenmüller; Elke Wintermeyer; Jürgen Machann; Birgit Linkohr; Annette Peters; Fabian Bamberg; Christopher L Schlett Journal: Eur Radiol Date: 2020-02-21 Impact factor: 5.315
Authors: Nicola Napoli; Manju Chandran; Dominique D Pierroz; Bo Abrahamsen; Ann V Schwartz; Serge L Ferrari Journal: Nat Rev Endocrinol Date: 2016-09-23 Impact factor: 43.330
Authors: Janina M Patsch; Xiaojuan Li; Thomas Baum; Samuel P Yap; Dimitrios C Karampinos; Ann V Schwartz; Thomas M Link Journal: J Bone Miner Res Date: 2013-08 Impact factor: 6.741
Authors: Kerensa M Beekman; Martine Regenboog; Aart J Nederveen; Nathalie Bravenboer; Martin den Heijer; Peter H Bisschop; Carla E Hollak; Erik M Akkerman; Mario Maas Journal: Front Endocrinol (Lausanne) Date: 2022-04-27 Impact factor: 6.055