Literature DB >> 34599728

Gastroesophageal Reflux Disease, Esophagitis, and Barrett's Esophagus 3 to 4 Years Post Sleeve Gastrectomy.

Samer Elkassem1,2.   

Abstract

BACKGROUND: Sleeve gastrectomy (SG) has become the most popular bariatric procedure worldwide. However, SG is associated with de novo gastroesophageal reflux (GERD) and esophagitis, with concerns for progression into Barrett's esophagus (BE). The purpose of this study is to assess the clinical and endoscopic progression of GERD, esophagitis, and BE 3 to 4 years after SG.
METHODS: Fifty-eight patients (pts) were assessed with endoscopy preoperative and at 3 to 4 years post SG, representing 44.9% follow-up. Endoscopy was offered to all SG pts regardless of symptoms. Outcomes including percent total weight loss (%TWL), PPI use, esophagitis progression, de novo reflux, and BE formation.
RESULTS: At post-op follow-up, the %TWL was 23%. The average BMI dropped from 49.07 to 37.5. De novo reflux developed in 13 pts (30.9%). Of the 16 pts with GERD pre-op, 37.5% improved, 25% had stable disease, and 37.5% had worsening symptoms. The rate of esophagitis nearly doubled from 37.9% pre-op to 70.6% post-op. A majority of post-op pts had mild esophagitis (87.8%), with 12.1% with LA classes C and D. Asymptomatic esophagitis was found in 68.2% of post-op pts. The incidence of BE was 12.7% post-op, with de novo BE developing in 4 pts, representing 7.2%.
CONCLUSION: SG is associated with increased rates of asymptomatic esophagitis and de novo reflux at 3 to 4 years post-op. De novo BE was detected as well, highlighting the importance of post-op screening. The majority of pts with GERD pre-op have stable disease or improve.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Barrett’s esophagus; De novo reflux; Endoscopy; Esophagitis; GERD; Sleeve gastrectomy

Mesh:

Year:  2021        PMID: 34599728     DOI: 10.1007/s11695-021-05688-0

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  48 in total

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Authors:  R M Humphrey; T C Hsu
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Review 5.  American Society for Metabolic and Bariatric Surgery updated position statement on sleeve gastrectomy as a bariatric procedure.

Authors:  Mohamed Ali; Maher El Chaar; Saber Ghiassi; Ann M Rogers
Journal:  Surg Obes Relat Dis       Date:  2017-08-22       Impact factor: 4.734

6.  Lack of correlation between gastroesophageal reflux disease symptoms and esophageal lesions after sleeve gastrectomy.

Authors:  Emanuele Soricelli; Giovanni Casella; Giovanni Baglio; Roberta Maselli; Ilaria Ernesti; Alfredo Genco
Journal:  Surg Obes Relat Dis       Date:  2018-02-13       Impact factor: 4.734

7.  Gastroesophageal Reflux and Laparoscopic Sleeve Gastrectomy: Results of the First International Consensus Conference.

Authors:  Ahmad Assalia; Michel Gagner; Marius Nedelcu; Almino C Ramos; David Nocca
Journal:  Obes Surg       Date:  2020-06-12       Impact factor: 4.129

8.  Fifth International Consensus Conference: current status of sleeve gastrectomy.

Authors:  Michel Gagner; Colleen Hutchinson; Raul Rosenthal
Journal:  Surg Obes Relat Dis       Date:  2016-01-25       Impact factor: 4.734

9.  Systematic Endoscopy 5 Years After Sleeve Gastrectomy Results in a High Rate of Barrett's Esophagus: Results of a Multicenter Study.

Authors:  Lionel Sebastianelli; Marine Benois; Geoffroy Vanbiervliet; Laurent Bailly; Maud Robert; Nicolas Turrin; Emmanuel Gizard; Mirto Foletto; Marco Bisello; Alice Albanese; Antonella Santonicola; Paola Iovino; Thierry Piche; Luigi Angrisani; Laurent Turchi; Luigi Schiavo; Antonio Iannelli
Journal:  Obes Surg       Date:  2019-05       Impact factor: 4.129

10.  IFSO Worldwide Survey 2016: Primary, Endoluminal, and Revisional Procedures.

Authors:  Luigi Angrisani; A Santonicola; P Iovino; A Vitiello; K Higa; J Himpens; H Buchwald; N Scopinaro
Journal:  Obes Surg       Date:  2018-12       Impact factor: 4.129

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Authors:  Belinda De Simone; Elie Chouillard; Almino C Ramos; Gianfranco Donatelli; Tadeja Pintar; Rahul Gupta; Federica Renzi; Kamal Mahawar; Brijesh Madhok; Stefano Maccatrozzo; Fikri M Abu-Zidan; Ernest E Moore; Dieter G Weber; Federico Coccolini; Salomone Di Saverio; Andrew Kirkpatrick; Vishal G Shelat; Francesco Amico; Emmanouil Pikoulis; Marco Ceresoli; Joseph M Galante; Imtiaz Wani; Nicola De' Angelis; Andreas Hecker; Gabriele Sganga; Edward Tan; Zsolt J Balogh; Miklosh Bala; Raul Coimbra; Dimitrios Damaskos; Luca Ansaloni; Massimo Sartelli; Nikolaos Parasas; Yoram Kluger; Elias Chahine; Vanni Agnoletti; Gustavo Fraga; Walter L Biffl; Fausto Catena
Journal:  World J Emerg Surg       Date:  2022-09-27       Impact factor: 8.165

  2 in total

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