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Literature DB >> 3459705

Infertility associated with two accessory bisatellited chromosomes.

M A Martín-Lucas, A Pérez-Castillo, J A Abrisqueta.

Abstract

Two extra bisatellited chromosomes identified as inv dup (15) (pter----q11.2::q11.2----pter) were found in an oligoasthenospermic male. Analysis of Ag-staining in the proband and in one fertile brother with a normal karyotype revealed that nucleolar organizer region (NOR) activity was significantly increased in the patient. The frequency of satellite associations was also significantly higher in the index case, but no correlation was found between NOR activity and acrocentric associations. These results suggest that extra NOR activity and the elevated frequency of satellite associations could predispose to gametogenic impairment.

Entities: Gene Species

Mesh：

Substances：

Year: 1986 PMID： 3459705 DOI： 10.1007/BF00291603

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

17 in total

1. Intercellular NOR-Ag-variability in man. II. Search for determining factors, clonal analysis.

Authors: O A Sozansky; A F Zakharov; S M Terekhov
Journal: Hum Genet Date: 1985 Impact factor: 4.132

2. Satellite association frequency and number of nucleoli depend on cell cycle duration and NOR-activity. Studies on first, second, and third mitoses of lymphocyte cultures.

Authors: J Sigmund; H G Schwarzacher; A V Mikelsaar
Journal: Hum Genet Date: 1979 Impact factor: 4.132

Infertility associated with two accessory bisatellited chromosomes.

1. Intercellular NOR-Ag-variability in man. II. Search for determining factors, clonal analysis.

2. Satellite association frequency and number of nucleoli depend on cell cycle duration and NOR-activity. Studies on first, second, and third mitoses of lymphocyte cultures.

3. Two kinships with accessory bisatellited chromosomes.

4. Chromosome aneuploidy in the father of a mongol.

5. Comparison of acrocentric associations in male and female cells. Relationship to the active nucleolar organizers.

6. Ag staining of the nucleolus organizer (NO) and its relationship to satellite association.

7. The genetic significance of accessory bisatellited marker chromosomes.

8. Supernumerary bisatellited chromosome in a family ascertained through a patient with Sturge-Weber syndrome.

9. Cytogenetic and clinical studies in five cases of inv dup(15).

10. New insights into the effects of extra nucleolus organizer regions.

1. Infertility and marker chromosomes: application of molecular cytogenetic techniques in a case of inv dup(15).

2. Characterization of seven DA/DAPI-positive bisatellited marker chromosomes by in situ hybridization.

3. Update and Review: Supernumerary Marker Chromosomes.

Review 4. Inv dup(15) supernumerary marker chromosomes.

5. Small supernumerary marker chromosomes (sSMC) in humans; are there B chromosomes hidden among them.