Christian Trujillo1, Brian Garnet2,3, Ali Vaeli Zadeh2, Gisel Urdaneta2, Michael Campos2,3. 1. Jackson Memorial Medical Center, Miami, Florida, United States. 2. Miami Veterans Administration Medical Center, Miami, Florida, United States. 3. University of Miami Miller School of Medicine, Miami, Florida, United States.
Abstract
BACKGROUND: Studies have shown a decline in hospitalizations due to acute exacerbations of COPD (AECOPD) during the coronavirus disease 2019 (COVID-19) pandemic. However, the impact of the pandemic in AECOPD of all severities in longitudinal cohorts of patients is lacking. METHODS: We conducted analysis of 123 individuals with COPD who have been followed since 2017. AECOPDs of mild (treatment at home), moderate (emergency department or urgent visit evaluation), and severe (hospitalization) type were assessed by chart review and patient interview. Compliance with preventive measures to avoid COVID-19 infection was assessed in 2020. Differences between the rate of AECOPD by year was analyzed as well as differences in preventive measures by COPD disease severity. RESULTS: During the COVID-19 pandemic in 2020, there was a significant reduction in AECOPDs in our cohort with 26 participants (21%) having an exacerbation compared to 46 (37%) in 2019, 52 (42%) in 2018, and 44 (36%) in 2017. Mean exacerbation rates decreased 54% overall and 74% in frequent exacerbators compared with the prior 3-year average. The decrease was noted in AECOPDs of all severities. Overall, there was a high rate of reported compliance with social distancing and face mask use that was significantly higher in the group with more severe COPD based on symptoms and forced expiratory volume in 1 second. CONCLUSIONS: Individuals with COPD, including frequent exacerbators, showed a marked decrease in AECOPD during the COVID-19 pandemic and high adherence to recommended preventive measures. Evaluation of the impact of preventive strategies on AECOPD in a non-pandemic setting may be of value and requires further study. JCOPDF
BACKGROUND: Studies have shown a decline in hospitalizations due to acute exacerbations of COPD (AECOPD) during the coronavirus disease 2019 (COVID-19) pandemic. However, the impact of the pandemic in AECOPD of all severities in longitudinal cohorts of patients is lacking. METHODS: We conducted analysis of 123 individuals with COPD who have been followed since 2017. AECOPDs of mild (treatment at home), moderate (emergency department or urgent visit evaluation), and severe (hospitalization) type were assessed by chart review and patient interview. Compliance with preventive measures to avoid COVID-19 infection was assessed in 2020. Differences between the rate of AECOPD by year was analyzed as well as differences in preventive measures by COPD disease severity. RESULTS: During the COVID-19 pandemic in 2020, there was a significant reduction in AECOPDs in our cohort with 26 participants (21%) having an exacerbation compared to 46 (37%) in 2019, 52 (42%) in 2018, and 44 (36%) in 2017. Mean exacerbation rates decreased 54% overall and 74% in frequent exacerbators compared with the prior 3-year average. The decrease was noted in AECOPDs of all severities. Overall, there was a high rate of reported compliance with social distancing and face mask use that was significantly higher in the group with more severe COPD based on symptoms and forced expiratory volume in 1 second. CONCLUSIONS: Individuals with COPD, including frequent exacerbators, showed a marked decrease in AECOPD during the COVID-19 pandemic and high adherence to recommended preventive measures. Evaluation of the impact of preventive strategies on AECOPD in a non-pandemic setting may be of value and requires further study. JCOPDF
Authors: Weihua Hu; Minglin Dong; Mengqing Xiong; Dong Zhao; Yang Zhao; Mengmei Wang; Tao Wang; Zhenlian Liu; Li Lu; Ke Hu Journal: Int J Chron Obstruct Pulmon Dis Date: 2020-09-23
Authors: Firoozeh V Gerayeli; Stephen Milne; Chung Cheung; Xuan Li; Cheng Wei Tony Yang; Anthony Tam; Lauren H Choi; Annie Bae; Don D Sin Journal: EClinicalMedicine Date: 2021-03-18
Authors: King Pui Florence Chan; Ting Fung Ma; Wang Chun Kwok; Jackson Ka Chun Leung; Ka Yan Chiang; James Chung Man Ho; David Chi Leung Lam; Terence Chi Chun Tam; Mary Sau Man Ip; Pak Leung Ho Journal: Respir Med Date: 2020-07-12 Impact factor: 4.582
Authors: Francisco Montiel-Lopez; Daniela Rodríguez-Ramírez; Maricruz Cassou-Martínez; María Cristina Miranda-Márquez; Claudia González-González; Raúl H Sansores; María Eugenia Mayar-Maya; Rogelio Pérez-Padilla; Robinson Emmanuel Robles-Hernández; Ireri Thirion-Romero; Oliver Pérez-Bautista; Alejandra Ramírez-Venegas Journal: ERJ Open Res Date: 2022-10-10
Authors: Jonas Poucineau; Tristan Delory; Nathanaël Lapidus; Gilles Hejblum; Christos Chouaïd; Sophie Le Cœur; Myriam Khlat Journal: Front Med (Lausanne) Date: 2022-09-16